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KEPPRA TOXICITY

Tue, 04/24/2007 - 21:19
A week ago yesterday, April 16th, my daughter started having symptoms of a toxic level to Keppra, the anti-seizure medication she was taking. She said she had been very tired for a couple of weeks. Her dose was 1000mg twide daily. She said she felt lightheaded & dizzy. She said she was having trouble processing information---like she was "high". That next morning she had a Keppra level drawn. Keppra was decreasd to 500 twice daily. By the next day she was having trouble speaking: slurred speech, speech arrest & stuttering with unsteady gait. At that point she went to the ER. She had a CT of her brain which was normal. She was admitted to the hosp. She had an EEG which was abnormal. She had a MRI of the Brain & an MRA, both which were normal. On 4-20 Keppra came back > 150. (Normal is 20-30). Last Keppra level was 3-24-07 & it was 48. The doctors there have never seen a Keppra level this high. Is it possible to network & see how long it will take the Keppra to leave her body? She has to walk with a walker. Her legs are too weak to support her without the walker. Her speech remains impaired with speech arrest & stuttering, plus it is very slow. ANYONE EVER HEARD OF SUCH A HIGH LEVEL??? Any treatment???

Comments

My dad is 75 done fine after

Submitted by Jonesvillegirl on Fri, 2019-07-19 - 09:44
My dad is 75 done fine after surgery for several days then i think when the keppra levels set in kept increasing them 3000 mg 1500 twice a day. He was lethargic al.ost to me i. A comotisis state never seen him this way yrs he is older yes he had surgery but he was ok right after surgery they automatically reduced him 1000 after being re admitted took him down slowly i guess and cut him off he still not his self been almost 2 weeks im worried sick they done sonething bc he was fine .is 3000 mg normal for a elderly person he has become bed riddin not eating or drinking now of course he is weak  he is down like never before i think it maybe kepora only thing that changed after surgery

Oh, my God!   My husband lost

Submitted by swfloridacoast on Mon, 2018-04-16 - 01:31
Oh, my God!   My husband lost all his strength, other cancer patients have been helping him in and out of radiation treatment.  I have  had  EMT's to the house for lift assists. With all the other GBM diagnosis and treatment issues, this seems to describe what has happened to him.  I will take it up with his doctors in the morning, thank you for having this info here. 

I'm 22 I've had seizures as

Submitted by Delana22 on Mon, 2018-04-23 - 22:32
I'm 22 I've had seizures as long as I can remember everytime I take my keppra I start to get a really lod ringing in the ears and I get very dizzy my neurologist said I dont have seizures I have whats called anxiety seizures anyone have info on this

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