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KEPPRA TOXICITY

Tue, 04/24/2007 - 21:19
A week ago yesterday, April 16th, my daughter started having symptoms of a toxic level to Keppra, the anti-seizure medication she was taking. She said she had been very tired for a couple of weeks. Her dose was 1000mg twide daily. She said she felt lightheaded & dizzy. She said she was having trouble processing information---like she was "high". That next morning she had a Keppra level drawn. Keppra was decreasd to 500 twice daily. By the next day she was having trouble speaking: slurred speech, speech arrest & stuttering with unsteady gait. At that point she went to the ER. She had a CT of her brain which was normal. She was admitted to the hosp. She had an EEG which was abnormal. She had a MRI of the Brain & an MRA, both which were normal. On 4-20 Keppra came back > 150. (Normal is 20-30). Last Keppra level was 3-24-07 & it was 48. The doctors there have never seen a Keppra level this high. Is it possible to network & see how long it will take the Keppra to leave her body? She has to walk with a walker. Her legs are too weak to support her without the walker. Her speech remains impaired with speech arrest & stuttering, plus it is very slow. ANYONE EVER HEARD OF SUCH A HIGH LEVEL??? Any treatment???

Comments

I just had my keppra level

Submitted by HLewis on Sat, 2019-04-13 - 08:54
I just had my keppra level checked and it came back 56.7. Every time mine gets checked it’s over 50 and this is the highest I’ve ever seen it. I’ve been off and on so many different seizure medications I don’t know which one is doing what to me anymore. I just seen my neurologist Thursday and he’s taking me off zonegran and lamictal and putting me back on topamax. I’m also staying on keppra and klonopin. I go to Cleveland Clinic and they don’t seem concerned with how high my keppra levels are. I take 1500mg twice daily. 

I also have spots on my legs

Submitted by deannazopp on Mon, 2019-04-22 - 10:26
I also have spots on my legs and arms similar to bruises from what was told to be toxicity

How about you not be a jerk?

Submitted by nbasow on Tue, 2019-04-16 - 18:59
How about you not be a jerk? I have both epilepsy and pseudoseizures, which are not "pretend seizures", they feel exactly the same as actual seizures and are absolutely awfulSo, how about you you can have my epilepsy, benzo dependence (which by the way, I'm coming off of benzos right now, it's called tapering and if you actually want to do it, you can, you're choosing to stay on them, so maybe what you actually have is substance-use disorder, in which case, get yourself some help), legitimate OCD, PTSD, Bipolar I with psychotic features, and multiple other chronic illness, and I'll take your epilepsy and panic disorder and I'll not be a jerk to other hurting people?

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