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KEPPRA TOXICITY

Tue, 04/24/2007 - 21:19
A week ago yesterday, April 16th, my daughter started having symptoms of a toxic level to Keppra, the anti-seizure medication she was taking. She said she had been very tired for a couple of weeks. Her dose was 1000mg twide daily. She said she felt lightheaded & dizzy. She said she was having trouble processing information---like she was "high". That next morning she had a Keppra level drawn. Keppra was decreasd to 500 twice daily. By the next day she was having trouble speaking: slurred speech, speech arrest & stuttering with unsteady gait. At that point she went to the ER. She had a CT of her brain which was normal. She was admitted to the hosp. She had an EEG which was abnormal. She had a MRI of the Brain & an MRA, both which were normal. On 4-20 Keppra came back > 150. (Normal is 20-30). Last Keppra level was 3-24-07 & it was 48. The doctors there have never seen a Keppra level this high. Is it possible to network & see how long it will take the Keppra to leave her body? She has to walk with a walker. Her legs are too weak to support her without the walker. Her speech remains impaired with speech arrest & stuttering, plus it is very slow. ANYONE EVER HEARD OF SUCH A HIGH LEVEL??? Any treatment???

Comments

I am taking Keppra since I

Submitted by Arindam1995 on Sat, 2017-04-15 - 13:53
I am taking Keppra since I was 13 year old, till now I am taking this medicine 500mg twice daily, Their are many side effects, most dangerous is suicidal behaviour. You can't remember anything what you learn 1 day ago or can't even remember your telephone number. Now I can't go outside with out have my daily dose it like a narcotic drug, whenever I stops my dose for a month, severe seizure happen, even I suddenly freezes and fall in a public place no one touched me. I lay down for 30 minutes like dead body no one help me. So Doctor suggest me to take the medicine till my death. Hope for best. Since this incident I am unable to go outside without my parent. I can't marry because it's a taboo in Indian society. I don't know why I am blessed with this type of diseases/ malfunctioning.  Arindam DiseasesIndia, Kolkata

If you dont mind me asking

Submitted by Lyss_2010 on Wed, 2019-04-10 - 01:40
If you dont mind me asking did she pass away from the keppra? Or seizures. Im worried im taking to much keppra and not feeling well i get dizzyy and my hearing goes and breathing slows down when i take it so i go to bed. 

This whole week, I've had

Submitted by favored75 on Sat, 2019-10-05 - 15:01
This whole week, I've had more & more issues with drowsiness, tiredness, & an inability to focus & concentrate. Today I began to noticing my speech beginning to slur. Thot it strange, but then I read this text. The keppra was increased from 875mg to 1000mg. While this is going on, I have also decreased Tegretol from 1000 mg to 800mg. Began having headaches when the increase began, but they went away after 2 wks. Thought I'd begin feeling better, but that hasn't happened. Now my days are running into each other. I even had a seizure but didn't know it at the time. I walk in my seizures from room to room. On that day, I was reaching for a roll of toilet paper. Time lapse occurred, but wasn't aware it occurred at the time because I was so tired. My next memory was of me being in the living room sitting on the couch. It was only much later when I returned to the bathroom needing a roll of toilet paper, that I found it in the bathtub. That was the sign I needed to let me know I'd had a seizure. Will have to talk to the doctor again abt the effects the medicine has been having on me. Can't keep going like this. I'm just as tired in the morning as I am at night.

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