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EEG questions -- Temporal lobe, etc.

Sat, 12/04/2004 - 21:25

Hi, folks. I am new here, so please bear with me!

My second-opinion epileptologist received two video-EEG CDs to examine. She wrote notations regarding right temporal lobe sharp waves or spikes and intermittent left temporal lobe slowing. A theta rhythm in the left temporal lobe and left parietal lobe was also noted, though it was most likely the result of a postictal state. This is based on the order in which it followed a clinical event. (This can also result from drugs, early sleep, etc., I am told.)

The EEG also detected seizures during sleep. I knew that I was having these -- by the way I felt in the morning and, later, how my fiancee would describe their generalization. (She has generalized epilepsy, secondary to a left frontal lobe, benign tumor.) Is there any part of the brain from which these most commonly originate? I was just wondering. Has anyone else out there had this detected and, if so, were you given any more information?

I also have questions about discharges from sphenoidal leads. Since the physician said it was possible that I had a right hippocampus with decreased volume, and she saw sharp waves or spikes from the right sphenoidal lead (SP2), does that lead to the right temporal lobe being more of an epileptogenic focus? There was left temporal lobe slowing -- and possible parietal lobe slowing -- so who knows. Physicians postulate in literature I have read that sharp waves are often seen coming from the sphenoidal leads in temporal lobe epilepsy. ...

She really is the first epileptologist to review more than one of my MRIs but I wonder why she is the first to even mention the possible loss of right hippocampal volume. I had a cleanly cut temporal lobe protocol MRI this year at another hospital that showed no abnornmalities. Is this, on her part, what someone calls an "educated guess?" Strangely, she is the same epileptologist who is sending a report to my mother's neurologist about a possible epilepsy diagnosis amid questions about Alzheimer's Disease.

So far, my regular epileptologist has diagnosed me with partial-onset, refractory epilepsy, with simple partial and complex partial seizures. (Although, I have had myoclonic-type seizures since 1988 -- which are now under control.) I just have a lot of questions. ...

Thanks!

Labspanielmix

Comments

RE: EEG questions -- Temporal lobe, etc.

Submitted by mexican_fire on Sat, 2004-12-04 - 21:25

Hi Labspanielmix,

It is Sheeba from EFA.  You surprised me, I didn't think you knew about this site.

I have info for you about some of what you are asking about.

You were asking about EEG slowing.  The rhythm of the normal EEG varies with the person's age, and differs depending on whether the person is awake, drowsy, or asleep.

There are well established limits for these variatations in rate and rhythm. 

A VERY COMMON cause pf slowing  is POST-ICTAL, occuring after a seizure due to inhibition of the firing of neurons.  It may last several hours.  Posti-ictal slowing is best diagnosed by its diappearances soon after the seizure.  If slowing lasts for days after a seizure, further evaluation is necessary.

Focal slowing should always be of concern and requires CAREFUL evalutaion, because it may occur in association with a local disturbance of the brain, such as a concussion, stroke, or a tumor.

Generalized slowing signifies disturbed brain function caused by acute distubances of whole brain function, for example, chemical disturbances, lack of 02, infection, or severe head injury with loss of consiousness.

Spikes are caused when the cells fire simultaneously.  A spike is a mini-electrical seizure.  Only if enough cells fire does a true CLINICAL seizure occur.  Thus, repeated spikes coming from a particular area represent the local response to a provocation there, an epileptic focus or scar.  In a person who has had a focal seizure, spikes may indicate the area that the seizure originated or started.  Multifocal spikes suggest that there are many abnormalities in the brain.

Spikes are not found to be important unless they are found consistently in one area on an EEG.

Does this help any??

Nancy

Hi Labspanielmix,

It is Sheeba from EFA.  You surprised me, I didn't think you knew about this site.

I have info for you about some of what you are asking about.

You were asking about EEG slowing.  The rhythm of the normal EEG varies with the person's age, and differs depending on whether the person is awake, drowsy, or asleep.

There are well established limits for these variatations in rate and rhythm. 

A VERY COMMON cause pf slowing  is POST-ICTAL, occuring after a seizure due to inhibition of the firing of neurons.  It may last several hours.  Posti-ictal slowing is best diagnosed by its diappearances soon after the seizure.  If slowing lasts for days after a seizure, further evaluation is necessary.

Focal slowing should always be of concern and requires CAREFUL evalutaion, because it may occur in association with a local disturbance of the brain, such as a concussion, stroke, or a tumor.

Generalized slowing signifies disturbed brain function caused by acute distubances of whole brain function, for example, chemical disturbances, lack of 02, infection, or severe head injury with loss of consiousness.

Spikes are caused when the cells fire simultaneously.  A spike is a mini-electrical seizure.  Only if enough cells fire does a true CLINICAL seizure occur.  Thus, repeated spikes coming from a particular area represent the local response to a provocation there, an epileptic focus or scar.  In a person who has had a focal seizure, spikes may indicate the area that the seizure originated or started.  Multifocal spikes suggest that there are many abnormalities in the brain.

Spikes are not found to be important unless they are found consistently in one area on an EEG.

Does this help any??

Nancy

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