VirtualPipeline OG-TW.jpg

What is the Pipeline Conference?

The Pipeline Conference showcases the latest developments in the epilepsy pipeline from preclinical to right before FDA approval. For 2020, the conference was held virtually.

Watch Sessions from the 2020 Pipeline Conference

Videos of various sessions are now available to watch. To view the available sessions, click links in the agenda below.

Agenda

Times are eastern time (ET). 

Day 1 – Thursday, August 27, 2020

Welcome and Introduction – 9:00-9:10 A.M.

  • Jacqueline French, MD, Chief Medical and Innovation Officer, Epilepsy Foundation  
  • Laura Thrall, President & CEO, Epilepsy Foundation

Session I: Diagnosis And Detection Devices Part I - 9:10-10:30 A.M.

Break – 10:30-10:50 A.M.

Session I: Diagnosis And Detection Devices Part II – 10:50-11:50 A.M

Session II/III (Parallel Tracks – 11:55 -12:30 P.M.)

Session II: Therapeutic Devices – 11:55-12:25 P.M. 

  • Therapeutic Device Pipeline Presentations
    • Cathodal Transcranial Direct Current Stimulation, tDCS, Neuroelectrics  –  Alexander Rotenberg MD 
    • DyNeuMo implantable device and platform, University of Oxford – Timothy Denison  
  • Q&A

Session III: COVID impact on recruitment to clinical trials – 11:55 -12:35 P.M. 

  • Presentation
    • Impact of COVID on Trials - Jeremy Levin, D.Phil, MB BChir, CEO Ovid Therapeutics
  • Panel moderated by Jacqueline French, MD, Chief Medical and Innovation Officer, Epilepsy Foundation with Jeremy Levin, D.Phil, MB BChir, CEO Ovid Therapeutics, Board Chair of the Biotechnology Innovation Organization (BIO), Melissa Maske, person living with epilepsy, and Pavel Klein, MD, Director, Mid-Atlantic Epilepsy and Sleep Center

Break – 12:35 -1:05 P.M.

Session IV: What We Still Need In Drugs For Focal Epilepsy – 1:05-3:10 P.M.

Break – 3:10-3:40 P.M   

Update From 2019 Shark Tank Winners – 3:40-4:10 P.M.

  • Update from 2019 winner #1 – Rachel Kuperman, Eysz 
  • Update from 2019 winner #2 – Jody McNannay, Curadite

2020 Shark Tank Competition – 4:10-6:00 P.M.

  • Moderator: Sonya Dumanis, PhD, Vice President of Research and Innovation, Epilepsy Foundation

    • NAO-VNS: A disruptive implantable neurostimulator for the treatment of epilepsy – Synergia Medical 
    • Minimally invasive implantable graphene electrodes – Brain Scientific Inc.  
    • Automated privacy enhancement for seizure videos – Mocxa  
    • A night-time SUDEP prevention device – Soterya 
    • Epilepsy emergency band – Keely McCarthy, mother of a child with epilepsy   
  • Discussion, voting, and awarding  

Award to Mary Ann Brodie: Accelerator Award Virtual Reception & Presentation – 6:00 P.M. 

Day 2 – Friday, August 28, 2020 

Platform Talks - 8:05-9:05 A.M. 

Parallel Tracks Session V/VI: 9:05 – 10:05 A.M.

Session V: Screening – 9:05-9:50 A.M.

  • Lectures 
    • Status report on NINDS Translational Epilepsy Research – Brian Klein PhD, NINDS 
    • Screening Across the Board: Where are we and where should we be going? – Mike Rogawski MD, PhD, University California Davis 
  • Pipeline Screening Presentation
    • NeuCyte Platform, NeuCyte – Thomas Portmann PhD, Associate Director, Head of Research
  • Q&A

Session VI: Data-Driven Solutions – 9:05-9:50 A.M.

  • Lectures 
    • What can we learn from aggregated data and why should we be capturing it? – David Voccola, Prometheus Research, Co-Founder 
    • Epilepsy Digital Experience Navigator (EDEN) – Jacqueline French MD, Chief Medical Innovation Officer, Epilepsy Foundation
    • Epilepsy Learning Healthcare System – Susan Herman, MD, Barrow Neurological Institute
  • Q&A

Break – 9:50-10:05 A.M.   

Session VII: Genetics – 10:05-11:05 A.M.

  • Lecture
  • Gene Modifying Therapies 
    • STK-001, Stoke Therapeutics – Barry Ticho MD, PhD, Chief Medical Officer
    • EXT101, Encoded Therapeutics – Stephanie Tagliatela, Chief Scientific Officer
  • Discussion Scaling approaches across genetic conditions
    • moderated by Ingrid Scheffer, MD with Barry Ticho, MD and Stephanie Tagliatela as key discussants

Session VIII: Rare And Ultra-Rare Diseases–Part I 11:05-12:20 P.M.

  • Discussion Moving Beyond Seizures. Moderated by Nicole Murray, Director, Epilepsy Foundation with key discussants Hillary Savoie, co-founder Cute Syndrome Foundation, Rima Nabbout MD, PhD Hôpital Necker – Enfants Malades, and Tracy Dixon-Salazar, PhD Director Research & Strategy, LGS Foundation

Lunch – 12:20-12:50 P.M.

Session VIII: Rare And Ultra-Rare Diseases–Part II 12:50-1:55 P.M.

Session IX: Reformulated Drugs And Other Therapies – 1:55 - 3:45 P.M.

  • Discussion - How to move a repurpose drug forward.  Panel moderated by Jacqueline French, MD, Chief Medical and Innovation Officer, Epilepsy Foundation with Greg Went, PhD, Former CEO of Adamas Pharmaceuticals and Mike Davis, UCB
  • Reformulated Drugs And Other Therapies Pipeline Presentation
    • Buccal diazepam, Aquestive Therapeutics – Michael Rogawski MD, PhD, Consultant 
    • Staccato alprazolam, Engage Therapeutics – Jouko Isojarvi MD, PhD, Chief Medical Officer 
    • Novel intramuscular diazepam, Xeris Pharmaceuticals – Anh Nguyen MD, Director, Strategy Operations 
    • CT-010, Cerebral Therapeutics – Dan Abrams MD, CEO 
    • The gut brain axis and epilepsy, Bloom Science – Christopher Reyes PhD, Co-Founder & CEO
    • Ganaxolone IV, Marinus Pharmaceuticals – Joe Hulihan, MD, Chief Medical Officer
    • NRL-3, Neurelis, Inc – Adrian L. Rabinowicz, MD, SVP, Clinical Development and Medical Affairs 
  • Q&A

Break - 3:45 - 4:00 P.M.

Platforms Talks 4:00 - 5:00 P.M.

  • Using Artificial Intelligence to Advance Epilepsy Treatment, Doc.AI, Sam De Brouwer, PhD, Co-Founder
  • Epistemic app, Epistemic, Paula Gomez, PhD, MBA, CEO and Co-founder
  • Reverse Engineering the Ketogenic Diet, Jim Sonner, MD, University of California, San Francisco
  • Can Machine Learning Improve Randomized Clinical Trial Analysis?, Daniel Goldenholz, MD, PhD, M HSc, Beth Isreal Deaconess Medical Center
  • Rare Epilepsy Landscape Analysis (RELA), Ilene Miller, JD

Closing Remarks – 5:00 P.M.

  • Jacqueline French MD, Chief Medical and Innovation Officer, Epilepsy Foundation 

Thank You to Our Sponsors

Thank you for your support to make the 2020 Epilepsy Foundation Pipeline Conference a successful event and your commitment to the epilepsy community.

2020 Pipeline Conference Sponsors

Watch Footage from the 2018 Pipeline Conference

Authored By: 
Epilepsy Foundation Research
Authored Date: 
05/2020
Reviewed By: 
Liz Dueweke MPH
on: 
Friday, December 11, 2020