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Weight Gain and Depakote

Sun, 02/06/2005 - 09:20

Okay so I went to see my neurologist yesterday and he told me some not so good things about my medicine.  Well lately I've been gaining weight..but I exercise everyday for 20 to sometimes even an hour a day and I lift weights.  I did the no carb thing but that was short lived but I still counted calories and all that and I havent lost any weight. 

My neuro was like "ah you gained weight" and I'm like yeah thanks for reminding me.  He said it's because of the Depakote..I was pissed cuz I forgot about that side effect.  And he said I can never go off of the depakote b/c when I was just on lamictal I kept having seizures.  So I heard Topamax makes you lose weight instead of gain like on depakote.  I was wondering..if you have JME-can you take topamax instead of depakote???

Comments

Re: RE: Weight Gain and Depakote

Submitted by bjoy on Thu, 2006-09-07 - 19:17
Hi, I know you posted this a loooooong time ago, but I just came across it as I'm pretty new to this site. I'm a 27 f with JME and have been taking Depakote for 11 years with great success, no tonic clonics and only moderate myoclonic jerks. However, I'm in the process of changing over to Keppra because the side effects stink! At first I did okay with the weight gain, but lately it's been hard to keep off...I'm always having this "full" feeling in my body and I've gained about 15 pounds. I'm taking 750mg of Depakote, and can't wait to start taking less. I was wondering how your seizure control has been on the Keppra/Depakote combo? Have you maintained your weight loss? If you have any advice, let me know, thanks! Hope you are well.

RE: Weight Gain and Depakote

Submitted by maddy2by4 on Mon, 2005-03-21 - 02:49

After brain surgeryIn 1995(repaired an A.V. Malformation), scar tissue that developed caused me to have ongoing seizures. I was put on every anti-seizure drug at the time, but was allergic to all of them, except Depakote. Weight gain was the first side effect that I noticed from the drug. I have been on the Depakote until February of this year, when I heard that Topamax might control my seizures. This meant no more going in to get my valproic acid levels checked, no more being tired, and most importantly, I could lose the 50 plus pounds that I put on over the past ten years. After being on the Topomax for three weeks, I had a seizure. The first one in five years. I realized one thing for sure then. The weight gain sucks, but the grand-mals suck even more. I have not found a diet that seems to work miracles yet, but I am not giving up yet. For now it is smaller portions, and plenty of exercise. Atleast I can maintain my weight by doing this.

Take Care,

maddy 

After brain surgeryIn 1995(repaired an A.V. Malformation), scar tissue that developed caused me to have ongoing seizures. I was put on every anti-seizure drug at the time, but was allergic to all of them, except Depakote. Weight gain was the first side effect that I noticed from the drug. I have been on the Depakote until February of this year, when I heard that Topamax might control my seizures. This meant no more going in to get my valproic acid levels checked, no more being tired, and most importantly, I could lose the 50 plus pounds that I put on over the past ten years. After being on the Topomax for three weeks, I had a seizure. The first one in five years. I realized one thing for sure then. The weight gain sucks, but the grand-mals suck even more. I have not found a diet that seems to work miracles yet, but I am not giving up yet. For now it is smaller portions, and plenty of exercise. Atleast I can maintain my weight by doing this.

Take Care,

maddy 

RE: RE: Weight Gain and Depakote

Submitted by jinx1331xnij on Tue, 2005-03-22 - 13:08
From the time I was 15 on up to 27, depakote was the only aed I was taking. I actually lost wieght at first ( went from 110 to 95 in about 3 months), then had trouble maintaining a wieght that was even close to healthy ( I had trouble staying at 110, and am only 5'6"). I think it was because the depakote made me so sick, it was very hard for me to force myself to eat. Different aeds have different side effects on different people I guess. Now, taking lamictal and clonazepam, I stay between 115 and 120.

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