Diastat® AcuDial™ is a rectal form of benzodiazepine that can easily be administered by non-medical people outside of a hospital setting. This information will help people understand important facts about giving and using Diastat safely. People who are asked to give Diastat should receive one on one teaching from a doctor or nurse.


Some Facts

Diazepam rectal gel is commercially available under the brand name of Diastat® AcuDial™. The names Diastat and Diastat AcuDial refer to the same medicine. The AcuDial system is just a specific way of delivering the correct amount of the medicine.

  • Diastat has been approved by the FDA for use by family members and non-medical caregivers in the management of selected people with refractory epilepsy (2 years of age and older) who are on stable regimens of seizure medicines and who require intermittent use of diazepam to control bouts of increased seizure activity.
  • Diastat should be used with caution for people with breathing problems, elderly people, or females who are pregnant, nursing, or planning to get pregnant.
  • Most commonly, Diastat is used in children or people who are not able to take medicines by mouth or who find this way of giving medicine more helpful.
  • The medicine comes prepackaged in special applicators or syringes that are used to give the medicine rectally. Two syringes or applicators come in each package with lubricant and instructions on how to use it.
  • The dose of Diastat to use is prescribed according to body weight. Ask the doctor or nurse for specific instructions on when to use it and whether a second dose of medicine can be used. Make sure they know about weight changes as your child grows and can adjust the dose appropriately.
  • The AcuDial delivery system allows the pharmacist to set the applicators to deliver the prescribed dose. When picking up your medicine from the pharmacy, it is important to check the dose of Diastat with the pharmacist.
  • Diastat does not need to be refrigerated, but it is important to store it in a safe place, away from children. Each twin pack will last up to 4 years.
  • After the Diastat has been given, follow disposal instructions that come with the medicine.
  • Do not reuse syringes for any reason or save partial amounts of medicine for later use.


Authored by: Steven C. Schachter, MD | Patricia O. Shafer, RN, MN | Patricia M. Dean, ARNP, MSN | Joseph I. Sirven, MD on 11/2013