The Epilepsy Community Forums are closed, and the information is archived. The content in this section may not be current or apply to all situations. In addition, forum questions and responses include information and content that has been generated by epilepsy community members. This content is not moderated. The information on these pages should not be substituted for medical advice from a healthcare provider. Experiences with epilepsy can vary greatly on an individual basis. Please contact your doctor or medical team if you have any questions about your situation. For more information, learn about epilepsy or visit our resources section.

newly diagnosed

Tue, 11/07/2006 - 23:33
My son who just turned 11 has been diagnosed with generalized epilepsy. We noticed staring spells this past summer and by the end of summer they were becoming more dramatic. His EEG showed the spike wave for absence seizures. The pediatric neurologist our family physician referred us to started him on zonisamide, seven days later he had a tonic clonic seizure for the first time. they increased the zonisamide and a week later he had another one, the next day two more and the next morning another one. He was having seizures and sleeping more than he was awake. They started him then on Depakote through an IV 600mg. He is taking 250 mg (depakote ER) in the morning and 250 at night, plus 100mg of zonisamide at night. He did well for the first 3 days, then started having seizures again yesterday two bad ones. This morning he had one but less dramatic with a faster recovery, and really long absence type seizures in the early afternoon. Sorry this is so long but am wondering if anyone has any helpful info. I don't know if his seizures would have gotten worse anyway or if the zonisamide made them worse. I feel like I want to get him off of the zonisamide, but I am not a doctor and am probably just worried because they got worse after he took it. Any info would be appreciated!

Comments

Re: Hi .. I'd strongly advise

Submitted by mikec2 on Wed, 2006-11-08 - 09:22
Just a quick comment on drug indications. I think a lot of people put too much weight on the approved indications and whether something is a primary or secondary treatment. This is often simply a strategic decision made by the pharmaceutical company to get the drug to market as quickly as possible. Once it is in the toolkit of specialists, epidelogists for instance, there is little motivation for pharma companies to do expensive trials to get closely related indications. Off label use, or prescribing by physicians for different indications, then often becomes rampant, fueled by by word of mouth among docs or simple experimentation for what is known to be a safe and efficacious treatent in the category. This is common although it doesn't cover every situation.

Sign Up for Emails

Stay up to date with the latest epilepsy news, stories from the community, and more.