Follow your doctor's directions. Call if you have any questions. Usually, your doctor will tell you to start by taking one tablet—either 250 or 500 milligrams— two times each day. After a while, the doctor may gradually increase the dosage up to as much as 3000 milligrams per day to get better control of your seizures. To take that amount, you probably would take two 750-mg tablets, two times a day.
Most people swallow the tablets whole to avoid their bitter taste. But people who cannot swallow whole tablets can crush the tablet and mix it with food, or use the liquid form.
When measuring Keppra liquid, be sure to use a standard-size medicine spoon or dropper (not a regular teaspoon) to get the right amount every time.
It's OK to take Keppra either with food or without food, but it's a good idea to take it the same way every time. Taking Keppra with food does not change how much Keppra your body absorbs, but it does slow down the absorption a bit.
Be careful if the doctor writes a new prescription using a different kind of pill. For example, if you've been using 500-mg tablets and the new prescription is for 750-mg tablets, be sure you use the correct number. Don't automatically continue to use the same number of pills as before.
Don't take more than the doctor prescribes. If you think you've used one or two extra tablets or one extra spoonful of liquid, call your doctor for advice. For a larger overdose, call your local poison control center or emergency room right away, unless you have special instructions from the doctor.
Don't stop taking Keppra or change the amount you use without talking to the doctor first. Stopping any seizure medicine all at once can cause serious problems.
All forms of Keppra should be stored at room temperature, away from light and humidity. (Don't keep the pills in the bathroom if it's damp there.) Of course, keep all Keppra out of the reach of children.