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Lamictal and birth control pills

I was just wondering if anyone was on brith control as well as Lamictal. My neurologist said that there is no interaction, but I came across 2 studies on the interaction that stated that it decreased Lamictal concentration by almost half. I'm not sure if I should be worried to start the birth control.


I took my 17 year old to the OBGYN and he put her on Loestrin 24 FE she had 4 periods in two months and a small seziure...she was seziure free for 3 years and in jan she had a tonic-clonic they uped her dosage and was fine untill the birth control pill. So be careful and i did let the OBGYN know this and he said shed be fine well he was wrong!!!

Both drugs interact with each other and decrease the effectiveness of each other.  If taking Lamictal, you need to be on another form of birth control as well (i.e., condoms), or you may get pregnant. 

From medscape drug interaction checker:


Moderate Interaction
  Lamictal XR Oral and YAZ 28 Oral may interact based on the potential interaction between LAMOTRIGINE and HORMONAL CONTRACEPTIVES. 

Lamotrigine/Hormonal Contraceptives

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

MONOGRAPH TITLE: Lamotrigine/Hormonal Contraceptives

SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed.

MECHANISM OF ACTION: Hormonal contraceptives increase the clearance of lamotrigine. Lamotrigine may induce the metabolism of contraceptives.(1,2)

CLINICAL EFFECTS: Concurrent use of lamotrigine and hormonal contraceptives may result in decreased levels and effectiveness of both agents.(1,2)

PREDISPOSING FACTORS: The interaction is more severe in patients not taking carbamazepine, phenytoin, phenobarbital, primidone, or rifampin.

PATIENT MANAGEMENT: No adjustments to the recommended lamotrigine dose escalation guidelines should be necessary in patients taking hormonal contraceptives.(1)

In patients NOT taking carbamazepine, phenytoin, phenobarbital, primidone, or rifampin, the maintenance dose of lamotrigine may need to be increased by as much as 2-fold according to clinical response if oral contraceptives are initiated. If these patients stop taking hormonal contraceptives, the dosage of lamotrigine may need to be decreased by 50%.(1)

In patients taking carbamazepine, phenytoin, phenobarbital, primidone, or rifampin, no lamotrigine maintenance dosage adjustments should be necessary if hormonal contraceptives are initiated or discontinued.(1)

Patients should be instructed to promptly report any changes in their menstrual cycle, such as break-through bleeding.(1)


-simple partials, some generalized, frontal lobe, temporal lobe and myoclonic... and student nurse :o)

I wouldn't start yet. I am on Lamictal and have been told that the interaction of the pill and Lamictal cause BOTH to be less effective. I want to be on birth control and am currently getting the Depo Provera injection. It might be something to look into if you do not want to increase your Lamictal dosage. It's very simple and my neuoroligst who I've been seeing for 16 years and highly trust discussed it with me and it seemed like the best medicine for someone taking Lamictal. But there is one thing I would look into if you decided to do Depo Provera, usually the injection is about every 13 weeks(i think) but if you are on Lamictal and have Epilepsy you need to get the injection sooner, every 10 weeks i think. I don't remember the exact week amount but I definately know you need to get it sooner than those not on Lamictal.

Stoppen met roken Roken verhoogt de kans op verschillende vormen van kanker, waaronder long- en mondkanker. Ook andere ziekten zoals bronchitis komen vaker voor bij rokers dan bij niet-rokers. Stoppen met roken is dus goed voor uw gezondheid: op de lange termijn heeft u minder kans op ziektes en op de korte termijn bent u fitter en energieker.

I find conflicting info when I do a search also ! I'm not on either birth control or Lamictal, so can't give you any advice. You might check with your pharmacist and see what they have to say.

Good Luck,

"We are each of us angels with only one wing, and we can fly only by embracing each other." -lucian de crescenzo

Beautiful sentiment. 

Hormonal birth control can affect level of lamictal in the bloodstream, requiring adjustments in doses in some people. If someone has been on birth control and lamictal, then birth control is stopped, also need to watch to make sure lamictal level doesn't increase too much. Here is a link to general info on lamictal and birth control and other possible drug interactions -
Hope this helps! Resource Specialist

Lamictal may cause severe or life-threatening skin rash, especially in children and in people who are allergic to other seizure medications. Serious skin rash may also be more likely to occur if you are taking Lamictal together with valproic acid (Depakene) or divalproex (Depakote). Seek emergency medical attention if you have a fever, sore throat, swollen glands, and headache with a severe blistering, peeling, and red skin rash.
addiction treatment

Please check with another neurologist. My daughter who had controlled seizures for 2 years with lamictal recently started taking the birth control pill - Yasmin. After 10 days on the pill she had a breakthrough seizure. She had not contacted her neurologist because she was assured by her gyno that Yasmin would have no interaction with her Lamictal. After her breakthrough seizure she immediately stopped the Yasmin. The blood level of the Lamictal had dropped to 4.3 and 2 weeks later it returned to her normal level of 9.1.

Thank you. That is all I needed to here to make me stop considering the birth control pill. I also was going to start Yasmin as well. Sorry about your daughter having a breakthrough seizure. I've also been seizure free for 2 years and I don't want to jeopardize it. I appreciate all responses.

Diane works fine for me!
I have had epilepsy for 8 years now, and have used Lamictal (sometimes combined with others) the whole time. I have also used Diane as birth control and have had no problems (blood tests been fine).
About 4 months ago I stopped using Diane to check if Diane had any influence on by fits (still have some small fits when sleeping). Have not noticed any difference. Then started to use a new type called Cerazette. Am a bit worried if these pills are as safe as Diane.. With cerazette you dont get the period any more, and thereby have no "checks".. Does anybody have any experience with Lamictal and cerazette ?


I have been on lamictal for a little over 2 years and i just started taking ortho tri cyclin low about 10-11 months ago. i haven't had any problems with interactions on either side - i really like lamictal - i have been seizure free since i started taking it (400 mg a day) you should check with both doctors - everyones body reacts differently - i hope this helps a little. i know i was very nervous when i started taking the birth control at first .

I have been on Apri (sp?) and Lamictal at the same time. I have noticed no problems. I only take 100 mg bid, but I have been fine taking both.

I was told not to long ago by my neuro that they both cut each other in almost half! No wonder I got pg 2x's on birth control pills and have had more that enough aura seizures to last me forever. I am a faithful pill taker for all my meds, believe me so I know that I didn't skip a dose of BC at all. I wish I could find more information on it because I have had to pay out of pocket for other methods than the pill, ie, depo shot. I just recently have gotten off of that although it stays in system for like up to a year. i would like to get the non hormonal IUD but ins won't cover and I would like to appeal if I could get more information, any ideas??

I'm taking lamictal and used to take yasmin. I stop using it because as soon as my doctor switch me to lamictal he told me to stop taking it.I used yasmin because my period was so awful and painful thay my OBGYN prescribed it. I didn't used it for birth contro but still the reason my doctor told me to stop was because he informed me that the birth control pills tend to lower the effect of lamictal therefore if I insisted on taking Yasmin he needed to increase my lamictal dosage. I chose to stop taking yasmin because I feel that the less lamictal I have in my body the less side effects I'll have to deal with and also when it come my time to start a family I'll have less medicine in my body which will benefit my baby. I prefer to bare with the pain from my period.I hope that this info. helps you. Take care.

Hi Anamaria,

I'm taking Lamictal as well. Love it! From Spring 2003 to August of last year I was also on birth control called Ovral. After going off the pill, I was pregnant 2 months later. I don't recall any bad reactions or problems with the combination. I take 600mg a day. I have had a blessed pregnancy (no morning sickness or swelling!) Of course, everyone is different. I'm due to give birth on June 14th, baby and I are healthy! When you choose to start a family you will be directed to start taking Folic Acid (very important). I take 5mg a day along with my prenatal vitamins & Omega 3.

I was on Lamictal and the pill. My birth control was called Ovral. I had no bad reactions to the combo. I think it might have to do with the birth control you choose. My "cycles" were on the dot each month. Of course, everyone is different. Within 2 months of going off the pill it was confirmed that I was pregnant! Baby and I are healthy and I'm due to give birth June 14th.

I am a 17 year old girl and taking lamictal and i want to take the pill.My neurologist said if i am to on the pill he said to increase the dose of lamictal by at least 50 or 100mg.I am currently taking 200 in the morning and 200 at night.I dont know what to do my boyfriend doesnt want me to go on the pill but we have already been sexually intimate.I dont know what to do.Please if you have any ideas please feel free to contact me.

Hi, Im Ashley. Im 20 years old and have had seizures since 5th grade. I just switched from depakote to lamictal when I was 17. I take 200mg at night and 200 in the morning too. I chose not to take the pill, I chose the NuvaRing, it has a higher percentage against pregnancy. It is very effective. I haven't had any negative side effects with the Lamictal/NuvaRing combo. And my previous boyfriends couldn't even feel the ring during intercourse. Your period is regular, short, and light. Also they have IUDs now. If you don't know, they are placed inside of you by your OB/GYN. You cant feel it, except for the first day or so, there is cramping. But it is non-hormonal and there are 3 different ones. One lasts for 3 years, 5 years, and 10 years. If you do want to get pregnant, you go to the doctor and they just remove it. Piece of cake. You need to do what is best for you, not your boyfriend. I think he would be much happier if you DID NOT get pregnant, than if you did, especially this young. It would seriously screw your future plans up. If you have any more questions, you can email me at

Good Luck,


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