| Time (mins) | Intervention |
|---|---|
| 0 | Airway, breathing, circulation |
| History | |
| Trauma survey | |
| Oxygen | |
| Establish IV access | |
| 5 | Send blood sample for lab tests |
| Thiamine 100 mg IV Dextrose 50%, 50 mL IV | |
| Naloxone 2 mg IV (if indicated by history) | |
| 10 | Benzodiazepines: lorazepam 2 gm IV q 5 min (may be earlier, if possible) |
| Phenytoin load 20 mg/kg, or fosphenytoin | |
| 30 | Phenobarbital or benzodiazepine infusion (midazolam or diazepam) |
| EEG monitoring (if not yet begun) | |
| 60 | Pentobarbital coma Table: Pentobarbital-Induced Anesthesia |
| 80 | General anesthesia, neuromuscular blockade |
Table adapted from B Litt, GL Krauss. Pharmacologic Approach to the Acute Seizure Patient. In B Chernow (ed), Pharmacologic Approach to the Critically Ill Patient (2nd ed). Baltimore: Williams & Wilkins, 1988;484-506.
Reviewed By:
Steven C. Schachter MD
on:
Saturday, May 1, 2004
