Generic name | Brand name | Metabolism |
diazepam | Valium | CYP3A4/2C9/1A2 |
lorazepam | Ativan | CYP3A4, GT2B7 |
alprazolam | Xanax | CYP3A4/2C19 |
clonazepam | Klonopin | CYP3A3/4 |
oxazepam | Serax | |
chlordiazepoxide | Librium |
CYP = cytochrome P-450; GT = glucuronosyltransferase.
Adapted from: Koppel BS. Contribution of drugs and drug interactions (prescribed, over the counter, and illicit) to seizures and epilepsy. In: Ettinger AB and Devinsky O, eds. Managing epilepsy and co-existing disorders. Boston: Butterworth-Heinemann; 2002;163.
With permission from Elsevier (www.elsevier.com).
Reviewed By:
Steven C. Schachter MD
on:
Monday, March 1, 2004