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Contrast MRI and MRS any connection between the two?


I have personally gone through all these tests (MRIs + MRS) for myself as the first MRI showed a ring enhancing lesion. And differential diagnosis through an MRS and contrast MRI is the only way forward in such cases.
However, I have another question related to this- what if the MRS is done without a "contrast" MRI. Note that a regular MRI is available and then a MRS is done. As far as I understand MRS is highly directional and I am not sure if doing the MRS without knowing the exact location of the centre of the lesion (as a regular MRI might not be as clear if there is significant edema) would be very useful.
Can anyone confirm if this is correct? Does the edema surrounding the lesion make it difficult for MRS to be used effectively thus making a contrast MRI a necessity (or even a good to have) and/or having a contrast MRI results in hand make a difference to the MRS results?
My dad is now going through all these tests too as a ring enhancing lesion was detected in the first MRI too. But the doctors have been unable to reach a diagnosis yet!


Each test gives the doctors

Each test gives the doctors information.  Multiple ring-enhancing lesions of the brain are one of the most commonly encountered abnormalities on neuroimaging.Newer advanced diagnostic techniques, such as diffusion-weighted magnetic resonance imaging (MRI), perfusion-weighted MRI, magnetic resonance spectroscopy (MRS) and other tests.a ring enhancing lesion can cause many different ailments..Clinically, they manifest as recurrent seizures, visual impairment, focal neurological deficit and raised intracranial pressure (severe headache, vomiting and papilledema).  <<< just a few to noteSo yes different technology enhances the view of what can be seen on the brain.MRI's are far better then the test they had back in 1964 that gave the doctors what the MRI todays does. Believe me I would hesitate give that test to one of my enemies...  

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