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KEPPRA TOXICITY

Tue, 04/24/2007 - 21:19
A week ago yesterday, April 16th, my daughter started having symptoms of a toxic level to Keppra, the anti-seizure medication she was taking. She said she had been very tired for a couple of weeks. Her dose was 1000mg twide daily. She said she felt lightheaded & dizzy. She said she was having trouble processing information---like she was "high". That next morning she had a Keppra level drawn. Keppra was decreasd to 500 twice daily. By the next day she was having trouble speaking: slurred speech, speech arrest & stuttering with unsteady gait. At that point she went to the ER. She had a CT of her brain which was normal. She was admitted to the hosp. She had an EEG which was abnormal. She had a MRI of the Brain & an MRA, both which were normal. On 4-20 Keppra came back > 150. (Normal is 20-30). Last Keppra level was 3-24-07 & it was 48. The doctors there have never seen a Keppra level this high. Is it possible to network & see how long it will take the Keppra to leave her body? She has to walk with a walker. Her legs are too weak to support her without the walker. Her speech remains impaired with speech arrest & stuttering, plus it is very slow. ANYONE EVER HEARD OF SUCH A HIGH LEVEL??? Any treatment???

Comments

Keppra* 

Submitted by taravc on Sun, 2018-06-03 - 01:52
Keppra* 

My keppra dosage went from

Submitted by susan d on Sun, 2019-03-24 - 18:56
My keppra dosage went from 500 mg to 2000 mg bid (twice a day). Still having some seizures which my Dr says are likely anxiety related. Also taking cymbalta for depression and phenobarbital at night, but still not sleeping all night and then have trouble getting up and down. Walked a mile to my local library last week, and my legs are still twinging. The flash headaches i get are the scariest tho...it feels like a lightning bolt hits me and then it hurts for awhile.A lot of times i say the wrong words or it comes out in the wrong order.I told my sister of all the things I've lost i miss my brain the most. My concentration is horrible, and i get embarrassed cuz i live with my son and daughter in law and the have to remind me like Im a child to turn out lights 

My sister had a major seizure

Submitted by cgutmann on Fri, 2017-10-13 - 13:37
My sister had a major seizure a few days ago she went to the hospital. They tested her keppra level and I just got the results this morning. Her level is 48.1. Just left a message for her neurologist and I am waiting to here back. She has also been having trouble with her walking. Her legs are very weak and she keeps falling backwards. After this last seizure he added another seizure medication without checking her keppra level. She ended up having an allergic reaction to the medication. He put her on another seizure medication without checking her keppra level. Thank goodness the hospital checked it. She was in a very fragile state to begin with. 

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