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Lamictal and pregnancy

Mon, 02/07/2005 - 20:43

Hi everybody

I have juvenile myoclonic epilepsy. I am currently 32 weeks pregnant and take 300mg of lamictal daily and have remained seizure free and well so far. 

I am concerned about the long term side effects of lamictal on my baby if I breast feed. I have recently read a paper "Concerns regarding lamotrigine and breast feeding" by Liporace et al which makes me concerned about the babys ability to metabolise the drug. I now think that I do not wish to breast feed my baby, but I am wondering if my baby goes through withdrawel from lamictal in the early stages of life will he suffer long term side effects from this. I know that breast feeding and especially colostrum has long term benefits but i am cautious due to the lack of information about what process the baby will use to metabolise it and how the build up of the drug in his system might affect his growth and development.

Has anyone else information or experience of bottle feeding or breast feeding a baby after taking lamictal through the pregnancy.

Would be gretaful for any input on how they are and if you think they went through withdrawal or any other side effects.

Thanks

Bugsbunny

Comments

RE: Lamictal and pregnancy

Submitted by spygirljoan on Tue, 2005-07-05 - 18:00
Oh and by the way I read the article someone linked to about the five-year study -- and it said there was only a little over a year left in the study, so we won't have to wait that long!spygirljoan

RE: RE: Lamictal and pregnancy

Submitted by niceladyx5 on Sun, 2005-07-10 - 22:10

Hello All....new member, I have epliepsy since birth, had only 3 or 4 grand mal szs.

I have been on 250mgs Depakote almost all the time. My neuro took me off the medication when I first got pregnant in 1998. I took no medication for 3 months prior to getting pregnant and then throughout pregnancy. Had no problems what so ever, except a eposide of shaking after delivery.

Laste year we decided to get pregnant for the second time. MY neuro put me on 50mgs of Lamictal. I did not have any problems with the szs, but had some bad eposiodes of panic attacks. The neuro gave me Paxil to combat the panic attacks but that did not help. So we gave up that attempt to get progrnant.

Now we are planning on another child, my neuro has swithced me from 250 Depakote to Lamictal. She started me small with 25mg daily dose and has increased it now to 100mgs/day. But I still get the panic attacks. A simple task like rinsing dishes has become difficult to handle. I am on Paxil, but that does not help a bit. I am thinking of going back to depakote and give up on getting pregnant.

Has anyone else had any similar experiences with Lamictal ?. I have been taking Lamictal this time for about 3 weeks, di I need to give it more time for my biody to adjust to the change in medication?.

Thanks !

 

.

 

Hello All....new member, I have epliepsy since birth, had only 3 or 4 grand mal szs.

I have been on 250mgs Depakote almost all the time. My neuro took me off the medication when I first got pregnant in 1998. I took no medication for 3 months prior to getting pregnant and then throughout pregnancy. Had no problems what so ever, except a eposide of shaking after delivery.

Laste year we decided to get pregnant for the second time. MY neuro put me on 50mgs of Lamictal. I did not have any problems with the szs, but had some bad eposiodes of panic attacks. The neuro gave me Paxil to combat the panic attacks but that did not help. So we gave up that attempt to get progrnant.

Now we are planning on another child, my neuro has swithced me from 250 Depakote to Lamictal. She started me small with 25mg daily dose and has increased it now to 100mgs/day. But I still get the panic attacks. A simple task like rinsing dishes has become difficult to handle. I am on Paxil, but that does not help a bit. I am thinking of going back to depakote and give up on getting pregnant.

Has anyone else had any similar experiences with Lamictal ?. I have been taking Lamictal this time for about 3 weeks, di I need to give it more time for my biody to adjust to the change in medication?.

Thanks !

 

.

 

RE: RE: RE: Lamictal and pregnancy

Submitted by Robin on Mon, 2005-07-11 - 08:40
Nicelady...Don't be so quick to give up on another pregnancy.  May daughter was on Depakote for 8 years.  Her dosage was the same as yours.  She has a really good doctor and he talked several times to her about becoming pregnant while she was on the drug.  It's true there could be a higher rate of some birth defects.  but he felt the dosage she was on was not so large that the percentage was low.  He did tell her to plan, plan and plan the pregnancy so they would run tests on the baby as early as being six weeks pregnant.  If anything really bad showed up they could determine what to do at that time.  Spinal Bifida was the largest risk and even now he feels with them doing infeto and repairing the spine before a baby is born that even that can be corrected.  (That is being done at Venderbilt in Nashville and now have enough cases to document the childrens progress.  People magazine had an article on it about 5-6 years ago).  Anyway, she really did well on that medicine.  She is planning on becoming pregnant next year and is on a pre-natal vitamin and large dosage of folic acid already.  Her ob-gyn has asked that she try the Lamictal and see if they work and go on it instead of the Depakote.  She has finally gotten weaned into the Lactimal and we will see in time how it is working...before she gets pregnant.  She has told me several times since then that she really trusted her neur. and would have had children anyway on the depakote.  She just really would have had every test she could have.  And I tend to believe that the dosage was not huge and chances weren't as great as if she was on a much larger dose and that the doctor would have watched her pregnancy closely. 

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