Frequency and causes of seizures Seizures are common in mitochondrial disease, though a majority of patients do not have seizures. In one database of several hundred patients with mitochondrial cytopathies, about 40–50% have seizures.*...

Frequency Mitochondrial disease or cytopathy (from cyto-, cell, and -pathy, disease) is not uncommon. In three large population studies, approximately 1 person in 9,000 had either a disease-causing mitochondrial DNA mutation or...

Long-term use of phenytoin has been found to cause osteomalacia. Bone disease is even more likely if a combination of antiepileptic drugs is used. Patients taking phenytoin should...

People who have significant liver disease definitely should not take Depakene (valproic acid). Neither should anyone who has shown an allergy to it. It is very important to make...

Diastat should not be given to people who have an eye condition called acute narrow angle glaucoma. People with open angle glaucoma may use it. Extra caution is...