I have mild partial and complex temporal lobe seizures, and have been taking Keppra (generic) since 2006. I take 1000 mg 2x/day. My neurologist had me have my blood tested last year and this year, and last year it was fine. This year my liver enzymes were considerably elevated. He told me to avoid alcohol, not to take any Tylenol and continue the Keppra as prescribed. Subsequent liver tests have shown an improvement, but not back to normal.
I also seem to have developed a lot of allergies since 2006. I have hives on a regular basis--I get them from aspirin, ibuprophen, and clothing with elastic or materials such as Polarfleece. I never had them before.
I don't trust the Keppra any more. My doctor said that Keppra doesn't cause liver functions to be abnormal, but orders these liver function tests yearly. Why would he do that if it never causes problems?
I've cut my Keppra dose in half (on my own-without notifying my doctor) and cut drinking almost out completely. I never take Tylenol anyway, so that's not an issue. I have another blood test later this month and I'll be interested to see how it is.
Has anyone else experienced abnormal liver function tests from Keppra? If so, what was the outcome?