I have been taking Depakote for only a short time now and have experienced a few of the side affects listed. Ever since I started taking Depakote I have been really tense, agitated and short tempered. I don't recall my doctor listing this as a normal possible side affect, and haven't really found much info on it being a side affect of the drug. I was wondering if anyone else has experienced this same problem. Not sure if its from the meds, or if its just me trying to deal with all the new stressors in my life. I would appreciate any input. Thanks.