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shellep

keppra and psychotic behavior

my daughter is 11 and just started having grand mal seizures in may 08. in june she was put on keppra 500mg twice a day. a couple weeks ago she started having  what looked like focal seizures. but the drs say its not a seizure. they think its behavioral or maybe even hallucinations. if anyone has had this happen to them please help me. i and the neurologists have taken her off but im worried that the keppra may have caused permenant damage. she also had trouble walking and needed a wheelchair to get around as i cannot carry a 106lb child!

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Re: keppra and psychotic behavior

zay's mom  when my daughter has the "pseudoseizures" she seems to b fighting someone off of her. arms swinging and legs kicking with her head moving from side to side and up and down. crying and screaming also. i dont know what to do to help my child

 

Re: keppra and psychotic behavior

My daughter is also on Keppra and they actually increased it to try and control her absence seizures, but as they increased it so did the mood swings, fits, hitting, kicking, crying and so much more! It has been horrible. I called the dr on Friday and they decreased it again due to all of the side effects. If it were up to me, I would have her off of it. Im gonna see if they will swith to Zarontin for the Absence seizures. Good luck, I know its hard!

Jamie

Re: keppra and psychotic behavior

my daughter is just starting keppra, and all of a sudden she says that she hears voices in her head,  and is really drowsy.  has anyone else experience this?

 

 

Re: keppra and psychotic behavior

From what i have experienced the drowsiness is normal and should subside after some time. However, i also had severe issues with the moodiness and rage and all that stuff. I was on Dilantin for a short time but seized, and switched to depakote for about 6 years but had a couple seizures and side affects that were putting my overall health in danger. I sought the advice of an epileptologist as my neuro seemed indifferent to my concerns about the meds. I started keppra in november and got up to a full dose of 1500 mg a day. After about two months i started having rage and anger issues(which is not typical behavior for me) so i went and saw my dr and they are putting me on zonisamide. My advice would be to seek the advice of an epileptologist as they are a lot more knowledgeable about seizure disorders/medications than a regular neurololgist.

Re: keppra and psychotic behavior

my daughter has a similer problem but she also shaver and go to deep sleep for about 20 mintues after that, i was not sure if that is related to medicaition or something else. but she been in a number of medication she been kepper for a couple years and then we add depaken which was a big mistake she was get a lot of shakes with that and some small sezuire, now take her off of that add  lamictal instead of depaken still taking kepper do you know that screaming and crying is from kepper anybody report it or have got better when stop keppar please let me know think you

Re: keppra and psychotic behavior

Did they do an MRI? I would have them do an MRI if they did not and have them check for Chiari Malformation.

Re: keppra and psychotic behavior

I'm 23, and have been on keppra for about a year now, I don't think it's right to put a child on this stuff, I have had a big problem with trying to deal with the moodiness and depression this stuff causes along with the difficulty of trying to get through a post graduate college course. At least at my age I understand that it is the medication causing the problems it must be quite frustrating for a child to experience these things in their formative years, if an alternative is available take it!  I doubt the Keppra has caused any damage however as it is being praised for it's non-toxicity etc. Luckily I've been able to reduce my doseage and the side affects have also been reduced but not to a level that I am content with.  Seek an alternative.

Re: keppra and psychotic behavior

Did they ever do the MRI????

I highly suggest vitamin B for a way to counter act the keppra. We have had great luck with it controlling the mood swings in my 10 year old son. I can always tell if he does not take his one morning vitamin b pill.

Re: keppra and psychotic behavior

I am not sure if this hits on exactly what you are looking for, but I am 26 years old and was on Keppra for two weeks (the same dosage as your child) and it made me a maniac. I flat out told people to stay away from me until it was out of my system.

Re: keppra and psychotic behavior

zay's mom we have taken her off of keppra but the drs have her on topamax and lamictal. but she has still been having the pseudoseizures. the neurologists had me take her to psychiatrists who put her on zoloft and risperdal. the pseudos were under control for a week but they are starting again. she has started biting herself and others. she also is hitting and trying to hurt herself. now they want me to take her to a therapist. i dont know what is going on with my child. the drs say she is depressed but what can an 11yo be depressed about. well she started having seizures, my mom just finished chemo for breast cancer, my gma is terminal with colon cancer that has spread to her lungs and kidney. a little over a year ago we moved 700 miles from one state to another. and this past school year she changed schools where she left all her friends and is now the only girl in the class. but seriously is that enough to be stressed about. she wont talk about the stress she apparently having. i can not work when she is having these pseudoseizures because she can harm herself or others. in turn i am soo far behind in my bills. is there anyone who has any advice for me 

Re: keppra and psychotic behavior

My daughter is 20 & has been having psychotic behavior since last September.  In November they hospitalized her & took her off of everything but Kepra.  They sent her home saying everything was fine.  Then she began having pseudoseizures that were diagnosed as real seizures.  They increased the Kepra(The Dr. said that there was no way that the Kepra could be cause her psychotic behavior.)  She was finally hospitalized two weeks ago & they told me that as a mentally disabled individual she should never have been put on this med because she cannot express her feelings.  She is being stepped off of Keppra & being put on depakote.  In the mean time, she is biting herself, hitting me, & having many moments of mania.

I finally found a doctor that works outside of the box(with individuals that her not in the realm of sameness).  He is very slow giving meds but he is working with a behavioralist & I am being paid to stay at home with my daughter so that I don't have to work.  There are several programs out there that you can subcontract with & set your home up as a group home for your daughter & be paid by medicaid to work with her. You must have medicaid waiver for this to work.   It is listed as hard to handle care under the IRS statutes.  I was trained as a med aid, & other first aid.  I already had plenty of experience...lol

Re: keppra and psychotic behavior

can you please help me i want to does your get any services at home such as OT AND PT. AND how can i apply to stay home get pay to take care of her i will love to take care of my daughter instead of someone else. i am not currently work, i am just taking care of her anyways but i dont get pay and my husband and i having a trouble keeping up wtih bills and her needs. she also have diffeculity walking and speech. thank you

Re: keppra and psychotic behavior

My nephew is 19 yrs. of age and has down' syndrome.  He recently began having seizures, and as treatment his neurologist prescribed Keppra.  Within the span of one month's time, he began having extreme psychotic breaks.  Since then, the psychosis has increased in frequency and intensity, so his neurologist has stepped him off of the Keppra.  He is now about two weeks out from the complete removal of the Keppra from his treatment, but it seems as though this horrific drug has already taken it's awful toll.  A recent MRI now shows evidence of schizophrenia.  Before all this began, he was the most mild-tempered, sweet and gentle soul!  I've found through research that this is a drug that should never have been prescribed to him due to his developmental disabilities.... as he is completely incapable of communicating the horror he is experiencing in his mind.  We need help!!  As of today, he has been removed from his home, as he poses a danger to himself and his parents.  Is there any way to reverse the damage?.... Maybe through detoxification of the liver and/or the monitored use of B vitamins to replace those 'dumped' by the brain as a result of Keppra use.  I feel desperate!

Re: keppra and psychotic behavior

Hi

She needs girlfriends her own age at school in class. Boys at 11 years are not going to include her in their games or friendship circle.  Moving is very stressful to any child.  As an adult epileptic I need a calm, stable  environment and a few good friends.  The illnesses in your family may be upsetting her. Also, she needs you more than any one else does.  You are right, she has to open up to you so you can help her. Find a school with empathetic teachers and more girls.

That said, I went completely nuts on keppra. I can't imagine what a child must be feeling when all those crazy thoughts arise. I had the sense to realise it was the drug. She may not.

Re: keppra and psychotic behavior

Hi. I just wanted to mention that in the November/December 2008 issue of "Neurology Now" talks about these types of seizures.  They are called PNES. 

I just did a search and the November/December 2008 issue does not seem to be available online yet.

It states PNES are very real seizures, and it says that psychotherapy treatment is more beneficial than going to a psychiatrist.

---

Re: keppra and psychotic behavior

I was put on 200o mg of Keppra and started having serious mood issues over several months that got worst and worst. I know that the drug can have serious psychological side-effects. I'm sorry to hear that this has continued to affect her. Hopefully with time it might go away. How long has it been? I know after I reduced dosage I was lethargic, slurring my speech, and literally seemed drunk to people for a little while afterwards. Perhaps she needs to heal from whatever the effects of the Keppra were on her system.

Re: keppra and psychotic behavior

chalk me up as another in the Keppra = bad effects column

me: seizures started at age 38 (after some bad hockey injuries), diagnosed with E in 2008, on phenytoin.. then in 2010 also started levetiracetam (Keppra) and experienced one period soon thereafter I can only describe as literally "Mind-Blowing".. a brief psychotic period that's still like a smudge of dreamlike recollections.

I'm not sure what "I" was from the outside, from an observer's standpoint, but from "my" standpoint levetiracetam turned my mind into a nightmare of melted fragment-horror.

once an issue arises and the doctor says nothing more but to "bump up the Keppra dose", I say leave that doctor immediately and get off the Keppra ASAP.

Keppra/lev. has a known history of causing these types of problems.

If a doctor doesn't know that, or isn't able to consider the Keppra as problematic, as an issue, when its use is coincidental with the arising of a mood issue - then that doctor is not worth your time, or probably the paper his degrees are printed on, and has probably a vested interest of some sort in being a Keppra advocate.

it is my opinion that this issue should definitely be addressed if there is any co-incidence of Keppra use with sudden psychotic behavior

since being taken off levetiracetam I've been put on lamotrigine

Re: keppra and psychotic behavior

I was put on keppra for 1 week and was not even safe to be around. Severe rage issues. I had to stop myself from punching a fellow church member sitting behind me because he breathed on my neck. I almost lost it. I in visioned myself standing up on the pew and knocking this guys head off with one big sucker punch. I had to get up and leave the sermon. I had to stop keppra immediately. Then I got brain shocks that have still not gone away. It's been a year now and still have brain shocks every 10-15 seconds. There isn't anything they can do for them cause they can't see them on an EEG. I took an 8 day EEG video monitoring and the found zero abnormalities. I had 27 probes glued to my scalp the entire time hooked to 8 feet of wire and it was just enough slack to reach the bathroom. Be very careful with keppra. It's a very dangerous drug and can ruin your life. I've lost my career my house and praise the lord my wife is very supportive and helpful and understanding. I have a very short memory now. I can lose you in the middle of a conversation. I'll be talking to you and just totally lose it and my train of thought. It's embarrassing. I do not recommend this drug to anybody. I have about 10 seconds of concentration just long enough time to be hit with a multiple series of brain zaps. It's like getting shocked by an electrical outlet but right in my brain. I never heard of such a thing until I did research on them. They come from withdrawl of those types of meds. FYI be very careful

Re: keppra and psychotic behavior

My nephew is 19 yrs. of age and has down' syndrome.  He recently began having seizures, and as treatment his neurologist prescribed Keppra.  Within the span of one month's time, he began having extreme psychotic breaks.  Since then, the psychosis has increased in frequency and intensity, so his neurologist has stepped him off of the Keppra.  He is now about two weeks out from the complete removal of the Keppra from his treatment, but it seems as though this horrific drug has already taken it's awful toll.  A recent MRI now shows evidence of schizophrenia.  Before all this began, he was the most mild-tempered, sweet and gentle soul!  I've found through research that this is a drug that should never have been prescribed to him due to his developmental disabilities.... as he is completely incapable of communicating the horror he is experiencing in his mind.  We need help!!  As of today, he has been removed from his home, as he poses a danger to himself and his parents.  Is there any way to reverse the damage?.... Maybe through detoxification of the liver and/or the monitored use of B vitamins to replace those 'dumped' by the brain as a result of Keppra use.  I feel desperate!

 

Re: keppra and psychotic behavior

I started of seizures at 17 (simple partial, complex partial and grand mal).  I'm 34 now and have tried most drugs out there like dilantin, lamictal, neurontin, tegretol, tegretol XR, trileptal, and keppra.  The combination of trileptal and keppra are controlling my seizures, almost seizure free for 7 years in a few months.  I had heard about the moodiness and irritiability (putting it mildly) about Keppra, so I was nervous.  I take 2000mg of it daily, a lot basically.  I do have my moments when the smallest, insignificant things will set me off.  I have to catch myself so I don't scream and want to hit my co-worker or loved ones.  I sometimes just have to walk away and cool down.  I haven't had such severe episodes like what I've read, but I know they do happen for others.  My neurologist in works carefully about the moodiness issues when I talk with her and my epileptologist discussed it with me thoroughly also.  They felt it was worth a try.  I do take 5 mg of lexapro to help with moodiness and vitamin B, both doctors recommending is helping offset that effect.

If the effects are severe as what I've read, then I'd definitely get off the medication slowly and find something new to try.