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UPDATED: Sat, 09/29/2007 - 4:14am

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Sedz
Sedz

Rectal diazepam vs clonazepam oral drops

I have a question for any medical personnel who may view the forums - I was just wondering why doctors and specialists prescribe the rectal medications instead of something like the oral drops (for instance Rivotril (Clonazepam) which can be dropped inside the bottom lip and is absorbed via the mucus membrane)?

We recently had a new student enrol at our school and our action plan requires (if necessary of course) the administration of rectal diazepam. Not that this is a problem for anyone, but I just wondered why it is chosen over the oral choices.
Is it something to do with the strength of the dosage available, or do the others work faster/longer than clonazepam ?

I was just curious as the clonazepam wasn't mentioned to the parents but my sons specialist did prescribe it for him.
My son however, is not what you would consider a 'severe' case if there is such a thing. His seizures (thankfully) are semi controlled by Lamictal right now.

Anyone know why the rectal option seems to be preferred ?

Thanks

Jo

By Sedz at Sat, 09/29/2007 - 4:14am | 230 views | 2 comments

Recent Comments on this Discussion

Thanks so much for the prompt reply - I neglected to say in my post that we're from Australia so our drug availabilities are sometimes slightly different from the US.

As far as the person being able to take an oral med after a seizure, this is why the oral drops are so much easier than tablet or the tube/syringe between cheek and gum options.Five drops (or whatever the specialist recommended dosage is) on a spoon (just in case the bottle neck dropper is loose and falls out) and you drop it inside the bottom lip, no need for swallowing so there is a shorter time frame as it doesn't need to be digested.(1mL = 2.5mg clonazepam, 1mL = approx 25 drops)

I agree that hopefully someone will do the testing in the near future and make this option available in the States - as far as our specialist is aware, it is much faster working and longer lasting than Frisium (clobazam). I'm not sure whether he knows this via medical trials or just by experience. (Dr Jon Silberstein and his father Dr Peter Silberstein are at the forefront of epilepsy treatment in Australia and are the consultant specialists at all of our major hospitals in Western Australia. I'm sure they've both forgotten more than we'll ever learn about the condition!)
Also, just to ensure that the readers are aware that I am talking about the use of this drug for outside of hospital/clinic use by non medical personnel and obviously it doesn't replace the intravenous methods of drugs such as diazepam etc which can be administered by hospital or paramedic staff or by onsite school nurses if you're lucky enough to have one.

Thank you again for the reply, much appreciated,

Jo

Sedz