I am switching from Depakote to Topamax, and I have heard different stories of how people react to the drug. My Bro-in-law took it for migraines and HATED the side effects, but a lady who works with my hubby LOVES it. I usually don't have much of a reaction to meds, but we are trying something new because the Depakote was affecting my weight a little, but mostly it was because I feel a little foggy while I am on the Depakote. I would love to hear anyone else's Topamax stories, both good and bad. Thanks!