I am a 42 year old woman with epilepsy (JME, first diagnosed when I was 13); I have been taking depakote since I was approximately 23 or 24 and my seizures have been well controlled. When I was last at the neurologist she recommended that I think about taking another medication (she recommended keppra or lamictal although she seemed weighted to keppra) because of the correlation between depakote (and other seizure meds) and osteoporosis. I am concerned about this connection as I'm already at high risk for osteoporosis (my mom has it, both of my grandmothers had it) but at the same time it seems like keppra also has a lot of fairly serious risk factors..many of them psychological. I have suffered from depression throughout my life and I feel as if I have finally gotten it (pretty much) under control so anything that screws with my psychological make up is definitely fairly frightening. Also, in the literature that I've read it seems to be prescribed for partial seizures although that is not what I have (?). I would be particularly interested in hearing about any POSITIVE experiences with Keppra. I want to hear that it's great but the side effects sound pretty bad and the fact that it hasn't been on the market for that long also makes me apprehensive. Any input would be greatly appreciated.