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Jan 24, 2015
Singh RK, Joshi SM, Potter DM, Leber SM, Carlson MD, Shellhaas RA
Febrile infection-related epilepsy syndrome (FIRES) is a newly recognized epileptic encephalopathy in which previously healthy school-aged children present with prolonged treatment-resistant status epilepticus (SE). Su...
Jan 24, 2015
Coppola G, Natale F, Torino A, Capasso R, D'Aniello A, Pironti E, Santoro E, Calabrò R, Verrotti A
PURPOSE: The present study aimed to assess the impact of the ketogenic diet on arterial morphology and endothelial function of the big vessels of the neck and on cardiac diastolic function, in a cohort of epileptic chi...
Jan 22, 2015
Oikawa H, Tomatsu S, Haupt B, Montaño AM, Shimada T, Sly WS
Hypophosphatasia (HPP) is an inborn error of metabolism caused by deficiency of the tissue-nonspecific alkaline phosphatase (TNSALP), resulting in a defect of bone mineralization. Natural substrates for this ectoenzyme...
Jan 21, 2015
Ebus SC, Lambrechts DA, Herraets IJ, Majoie MJ, de Louw AJ, Boon PJ, Aldenkamp AP, Arends JB
PURPOSE: We examined whether early EEG changes in a 24-h EEG at 6 weeks of treatment were related to the later clinical response to the ketogenic diet (KD) in a 6-month period of treatment. METHODS: We examined...
Jan 21, 2015
Nei M, Ngo L, Sirven JI, Sperling MR
PURPOSE: The ketogenic diet is an alternative treatment for patients with refractory epilepsy. Most studies to date report dietary response in children. There are limited data evaluating the efficacy of the ketogenic d...
Jan 20, 2015
Chang P, Zuckermann AM, Williams S, Close AJ, Cano-Jaimez M, McEvoy JP, Spencer J, Walker MC, Williams RS
The medium chain triglyceride (MCT) ketogenic diet is a major treatment of drug-resistant epilepsy but is problematic, particularly in adults, because of poor tolerability. Branched derivatives of octanoic acid (OA), a...
Jan 15, 2015
Yeon GM, Lee YJ, Kim YM, Nam SO
OBJECTIVE: Few studies have been conducted among pediatric patients to examine clinical outcomes associated with the combined use of Oriental medicine and other therapies to treat epilepsy. The purpose of this study wa...
Jan 13, 2015
Desguerre I, Hully M, Rio M, Nabbout R
INTRODUCTION: Mitochondrial respiratory chain defects (RCD) often exhibit multiorgan involvement, affecting mainly tissues with high-energy requirements such as the brain. Epilepsy is frequent during the evolution of m...
Jan 13, 2015
Bertoli S, Trentani C, Ferraris C, De Giorgis V, Veggiotti P, Tagliabue A
OBJECTIVE: The only known treatment of glucose transporter 1 deficiency syndrome (GLUT-1 DS) is a ketogenic diet (KD), which provides the brain with an alternative fuel. Studies in children with intractable epilepsy ha...
Jan 13, 2015
Procaccio V, Bris C, Chao de la Barca JM, Oca F, Chevrollier A, Amati-Bonneau P, Bonneau D, Reynier P
Mitochondrial dysfunction has been reported in most neurodegenerative diseases. These anomalies include bioenergetic defect, respiratory chain-induced oxidative stress, defects of mitochondrial dynamics, increase sensi...

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