Mysoline must be introduced gradually, and a low starting dose is advisable. Here is an example of a typical schedule for building up to the desired level of Mysoline for an older child or adult:

• Days 1 to 3: 100 to 125 mg at bedtime
• Days 4 to 6: 100 to 125 mg each morning and evening
• Days 7 to 9: 100 to 125 mg morning, noon, and night
• Days 10 and later: 250 mg morning, noon, and night

Patients aged 8 or older usually take one 250-mg Mysoline tablet three or four times a day to maintain control of their seizures. Some people need to take more tablets, but the total dose should not exceed 2000 mg per day.

For children under 8 years of age, the usual dose for controlling seizures is 125 to 250 mg three times daily. The dose is usually calculated according to the child's weight, based on 10 to 25 mg of Mysoline per day for each kilogram (about 2.2 pounds) of the child's weight. Here is an example of a schedule that may be used to start a young child on Mysoline:

• Days 1 to 3: 50 mg at bedtime
• Days 4 to 6: 50 mg morning and evening
• Days 7 to 9: 100 mg morning and evening
• Days 10 and later: 125 mg three times a day to 250 mg three times a day

No one should stop taking Mysoline or change the amount they take without talking to their doctor first because of the risk of seizure exacerbation or status epilepticus.