Adults usually are told to start by taking 300 to 600 milligrams (mg) per day, divided into two doses. After about a week, the doctor probably will suggest taking a higher dose. The recommended dosage for most adults is 600 to 1,200 mg per day when oxcarbazepine is used alone. Higher dosages may be necessary when it used in combination with other seizure medicines.

Patients with poor kidney function generally should take only half as much. This also applies to many seniors with age-related changes in kidney function.

Those who have been taking another seizure medicine may be told to continue to take it in the same way as before, or the amount of the other medicine may gradually be reduced over several weeks to months. If the plan is to continue taking another medicine along with oxcarbazepine, blood tests may be needed to check the level of the other medication. Oxcarbazepine sometimes causes it to change.

The dose for children is calculated based on the child's body weight. Usually the doctor will prescribe 8 to 10 mg per kilogram (2.2 pounds) of weight to start, divided into two doses per day. This dose will be increased over a period of about 2 weeks. Because of the way their bodies process the medication, children who are 8 or younger may need a higher dose than older children.

Reviewed by Steven C. Schachter, MD
Submitted: 01/03/08