The process of absorbing, digesting, and excreting a medicine or food is called metabolism. The way the body metabolizes a particular medicine affects how often it must be taken. It also determines whether it will interact with other medicines or be affected by conditions such as liver disease.
Lyrica is not metabolized by the liver, and does not cause the liver to change how it metabolizes other medications.
When capsules are used, the amount of medicine in the blood will be highest after 1½-3 hours, depending on whether it is taken with food or not. The half-life of Lyrica (the amount of time it takes for the level in the blood to fall by 50%) is generally around 6 hours; therefore, Lyrica usually is taken two or three times a day to keep the level from dropping too low.
Because the body eliminates Lyrica through the kidneys, people with kidney disorders usually need less Lyrica and take it less frequently.
Reviewed October 2005 by Steven C. Schachter, MD, epilepsy.com Editorial Board.
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Created by at04/27/2007 - 3:04am|152 Views
Blog Posted To: a life with problems
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