Any time a doctor suggests a new prescription, be sure to talk about what other medicines, supplements, herbs, and vitamins are already being taken. Sometimes one kind of medicine changes the way another kind of medicine works in the body. If two kinds of medicine affect each other, the doctor may prescribe something else or change the amount to be taken.

How does Lamictal affect other medicines?
Lamictal has no effect on other seizure medicines.

How do other seizure medicines affect Lamictal?
Some other seizure medicines do affect the level of Lamictal in the body, either raising it or lowering it. Many of these interactions vary from person to person, however. Some may even vary from time to time for the same person. Make sure that your doctor is aware of all the seizure medicines you're using.

A few seizure medicines may reduce the level of Lamictal in the blood (only if valproate is not also being taken):

• carbamazepine (Tegretol, Tegretol XR, Carbatrol)
• phenytoin (Dilantin, Phenytek)
• phenobarbital
• primidone (Mysoline)

The seizure medicine that increases the blood level of Lamictal is:

• valproate (Depakote, Depakene, valproic acid)