Keppra XR is commonly prescribed for people over 65, but it's important for the doctor to be careful about how much Keppra XR these people take. When people are older than 65 or 70, their kidneys usually don't work as well as before. The kidneys are responsible for removing Keppra XR from the body, so it stays in the body longer. If a senior takes the amount of Keppra XR that is OK for most young people, the medicine will build up and may cause problems.

Seniors need to increase their dose more slowly than a younger person would.

Seniors also may be more sensitive to the side effects of Keppra XR. Some of the common side effects, like sleepiness, dizziness, or loss of strength, may worsen pre-existing problems. Seniors' greater risk of injury from falls or other accidents makes this an area of concern.

The lack of interactions between Keppra XR and other medicines is an advantage over most other seizure medicines commonly used by seniors.