After medicine is swallowed, it must be absorbed into the blood so it can move throughout the body. The process of absorbing a medicine or food, digesting it, and eliminating it from the body is called metabolism. The way the body metabolizes a particular medicine affects how often it must be taken. It also determines whether it will interact with other medicines or be affected by conditions such as disease of the liver or kidneys.Many other medicines are metabolized by the liver, but Neurontin is not. This is why it does not affect the way other medicines work, and they do not affect Neurontin. People with liver disease should be able to use it without trouble.
The body removes Neurontin through the kidneys, so people with kidney disorders need to be careful. To prevent too much Neurontin from building up in the body, they usually need to take less Neurontin and take it less often.
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