Safety and effectiveness of Keppra XR in persons below the age of 16 have not been established. 

 In children, regular Keppra has been used primarily to treat partial seizures, ones that begin in a limited area of the brain.

Wiht regard to regular Keppra, doctors figure out how much medicine to give to young children based mostly on their weight. To keep side effects at a minimum, the doctor probably will prescribe a low dose to start with and increase it slowly. Children usually start with a dose of 10 milligrams (mg) for each kilogram (kg, about 2.2 pounds) of their body weight per day. This would be 250 mg per day for a 55-pound child, for instance. Half this amount is usually given two times a day. After a gradual increase, most children do best taking about 20 to 40 mg per kg per day, Adjusted for weight, this is a little higher than the adult dose because children's bodies eliminate regular Keppra more quickly.