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Dec 4, 2014
Amari A, Turner Z, Rubenstein JE, Miller JR, Kossoff EH
PURPOSE: Previous research has indicated that children with seizures may prefer high fat foods - a preference compatible with ketogenic and modified Atkins dietary therapies. The purpose of this prospective study was t...
Dec 3, 2014
Hallböök T, Sjölander A, Amark P, Miranda M, Bjurulf B, Dahlin M
BACKGROUND: This Scandinavian collaborative retrospective study of children treated with ketogenic diet (KD) highlights indications and effectiveness over two years follow-up. METHODS: Five centres specialised ...
Dec 3, 2014
Simard-Tremblay E, Berry P, Owens A, Cook WB, Sittner HR, Mazzanti M, Huber J, Warner M, Shurtleff H, Saneto RP
PURPOSE: To determine the efficacy of the Modified Atkins Diet (MAD) and Ketogenic Diet (KD) in seizure control within a population of myoclonic-astatic epilepsy (MAE) patients. METHODS: This was a retrospectiv...
Dec 3, 2014
Caraballo RH, Flesler S, Armeno M, Fortini S, Agustinho A, Mestre G, Cresta A, Buompadre MC, Escobal N
The ketogenic diet (KD) has been used as an alternative treatment for patients with refractory status epilepticus (SE). PURPOSE: In this retrospective study we assess the efficacy and tolerability of the KD in ...
Dec 3, 2014
Wong VC, Fung CW, Kwong AK
BACKGROUND: Mutation of SCN2A, encoding for voltage-gated sodium channel type II alpha subunit, has been demonstrated in various epilepsy phenotypes, ranging from benign to severe epileptic disorders and recently this ...
Dec 3, 2014
Socała K, Nieoczym D, Pieróg M, Wlaź P
Although several studies have reported the acute anticonvulsant activity of caprylic acid in animal seizure models, little is known about the mechanism underlying this effect. Recently, the role of adenosine in the eff...
Dec 3, 2014
Mohammad SS, Coman D, Calvert S
Glucose transporter 1 deficiency syndrome (OMIM 606777) is a treatable epileptic encephalopathy caused by mutations in the SLC2A1 gene (OMIM 138140) causing impaired glucose transport into the brain. The classical phen...
Nov 22, 2014
Walker I, Said RR
It is unclear whether electrographic features are predictive of ketogenic diet efficacy and how evolution of electroencephalogram (EEG) findings correlates with clinical improvement. We aimed to identify predictors for...
Nov 22, 2014
Mikkelsen KH, Seifert T, Secher NH, Grøndal T, van Hall G
Context: Ketone bodies are substrates during fasting and when on a ketogenic diet not the least for the brain and implicated in the management of epileptic seizures and dementia. Moreover, D-β-hydroxybutyrate (HOB) is ...
Nov 19, 2014
Erbguth F, Himmerich H
"Healthy" diets and supplements are widely used for prevention and disease modification in vascular, inflammatory and degenerative neurological diseases. Apart from a large number of cross-sectional and prospective coh...