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Aug 26, 2017
Ruskin DN, Murphy MI, Slade SL, Masino SA
Prenatal factors influence autism spectrum disorder (ASD) incidence in children and can increase ASD symptoms in offspring of animal models. These may include maternal immune activation (MIA) due to viral or bacterial ...
Aug 19, 2017
Peng M, Yin N, Li MO
Mechanistic target of rapamycin complex 1 (TORC1) integrates nutrient signals to control cell growth and organismal homeostasis across eukaryotes. The evolutionarily conserved GATOR complex regulates mTORC1 signalling ...
Aug 17, 2017
Bruce S, Devlin A, Air L, Cook L
There are difficulties inherent in measuring Quality of life (QoL) in patients with chronic illness, including agreement on definitions of quality of life and the type of measure used, disease specific or generic. Well...
Aug 17, 2017
El-Rashidy O, El-Baz F, El-Gendy Y, Khalaf R, Reda D, Saad K
Many diet regimens were studied for patients with autism spectrum disorder (ASD) over the past few years. Ketogenic diet is gaining attention due to its proven effect on neurological conditions like epilepsy in childre...
Aug 12, 2017
Elia M, Klepper J, Leiendecker B, Hartmann H
BACKGROUND: Although a larger number of antiepileptic drugs became available in the last decades, epilepsy remains drug-resistant in approximately a third of patients. Ketogenic diet (KD), first proposed at the beginni...
Aug 12, 2017
Józefczuk J, Kasprzycka W, Czarnecki R, Graczyk A, Józefczuk P, Krzysztof M, Lampart U, Mrozowska-Ząbek E, Surdy W, Kwiatkowska-Graczyk R
We have analyzed concentrations of magnesium (Mg), calcium (Ca), copper (Cu), zinc (Zn) and iron (Fe) in hair of a group of 82 children with mental retardation, in which 9 patients suffered from epilepsy, 18 from the D...
Aug 12, 2017
Tan KN, Carrasco-Pozo C, McDonald TS, Puchowicz M, Borges K
The hypothesis that chronic feeding of the triglycerides of octanoate (trioctanoin) and decanoate (tridecanoin) in "a regular non-ketogenic diet" is anticonvulsant was tested and possible mechanisms of actions were sub...
Aug 10, 2017
Grocott OR, Herrington KS, Pfeifer HH, Thiele EA, Thibert RL
The low glycemic index treatment, a dietary therapy that focuses on glycemic index and reduced carbohydrate intake, has been successful in reducing seizure frequency in the general epilepsy population. Epilepsy is a co...
Aug 10, 2017
IJff DM, Postulart D, Lambrechts DAJE, Majoie MHJM, de Kinderen RJA, Hendriksen JGM, Evers SMAA, Aldenkamp AP
PURPOSE: The ketogenic diet (KD) is increasingly used for the treatment of refractory epilepsy in childhood because of the beneficial effect on seizure reduction. The aim of the current study was to objectively assess ...
Aug 10, 2017
Cervenka MC, Henry BJ, Felton EA, Patton K, Kossoff EH
OBJECTIVES: Over 250 medical centers worldwide offer ketogenic diets to children with epilepsy; however, access to these therapies has been extremely limited for adults until recent years. We examine our 5-year experie...