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Feb 3, 2015
Patterson EE
The mainstay of comparative research for epilepsy has been rodent models of induced epilepsy. This rodent basic science is essential, but it does not always translate to similar results in people, likely because induce...
Feb 2, 2015
Doksöz Ö, Güzel O, Yılmaz Ü, Işgüder R, Çeleğen K, Meşe T
BACKGROUND: Limited data are available on the effects of a ketogenic diet on dispersion duration of P-wave and QT-interval measures in children. We searched for the changes in these measures with serial electrocardiogr...
Feb 2, 2015
Ye F, Li XJ, Jiang WL, Sun HB, Liu J
BACKGROUND AND PURPOSE: Despite the successful use of a ketogenic diet in pediatric epilepsy, its application in adults has been limited. The aim of this meta-analysis was to summarize the findings of relevant publishe...
Feb 2, 2015
Gedik AH, Demirkol D, Tatlı B, Bayraktar S, Alkan A, Karabocuoglu M, Yuksel A
BACKGROUND: Refractory status epilepticus is a prolongation of status epilepticus despite anticonvulsant therapy with two or three medications in proper doses; it is defined as malignant status epilepticus if it takes ...
Jan 27, 2015
Borlot F, Tellez-Zenteno JF, Allen A, Ali A, Snead OC, Andrade DM
OBJECTIVES: Children with severe chronic epilepsy are living longer, and they eventually transition to the adult health care system. Additional research is required to better define the population that is being transfe...
Jan 27, 2015
Kim HJ, Kim HD, Lee JS, Heo K, Kim DS, Kang HC
PURPOSE: We investigated long term prognosis of Lennox-Gastaut syndrome (LGS) with active application of recent advanced treatment modalities such as ketogenic diet (KD) or epilepsy surgery (ES). METHODS: We re...
Jan 27, 2015
de Kinderen RJ, Postulart D, Aldenkamp AP, Evers SM, Lambrechts DA, Louw AJ, Majoie MH, Grutters JP
PURPOSE: The objective of this study was to estimate the expected cost-utility and cost-effectiveness of the ketogenic diet (KD), vague nerve stimulation (VNS) and care as usual (CAU), using a decision analytic model w...
Jan 24, 2015
Singh RK, Joshi SM, Potter DM, Leber SM, Carlson MD, Shellhaas RA
Febrile infection-related epilepsy syndrome (FIRES) is a newly recognized epileptic encephalopathy in which previously healthy school-aged children present with prolonged treatment-resistant status epilepticus (SE). Su...
Jan 24, 2015
Coppola G, Natale F, Torino A, Capasso R, D'Aniello A, Pironti E, Santoro E, Calabrò R, Verrotti A
PURPOSE: The present study aimed to assess the impact of the ketogenic diet on arterial morphology and endothelial function of the big vessels of the neck and on cardiac diastolic function, in a cohort of epileptic chi...
Jan 22, 2015
Oikawa H, Tomatsu S, Haupt B, Montaño AM, Shimada T, Sly WS
Hypophosphatasia (HPP) is an inborn error of metabolism caused by deficiency of the tissue-nonspecific alkaline phosphatase (TNSALP), resulting in a defect of bone mineralization. Natural substrates for this ectoenzyme...