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Nov 7, 2016
Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V
Ketogenic Diet used to treat refractory epilepsy for almost a century may represent a treatment option for mitochondrial disorders for which effective treatments are still lacking. Mitochondrial complex I deficiencies ...
Nov 5, 2016
Kim J, Yin T, Shinozaki K, Lampe JW, Becker LB
Accumulating evidence illustrates the beneficial effects of dietary docosahexaenoic acid (DHA) on cardiovascular diseases. However, its effects on cardiac arrest (CA) remain controversial in epidemiological studies and...
Nov 3, 2016
Tian T, Li LL, Zhang SQ, Ni H
The divalent cation zinc is associated with cortical plasticity. However, the mechanism of zinc in the pathophysiology of cortical injury-associated neurobehavioral damage following neonatal seizures is uncertain. We h...
Nov 2, 2016
Bejarano E, Rodríguez-Navarro JA
Autophagy is a catabolic pathway responsible for the maintenance of the tissue and organism homeostasis. Several amino acids regulate autophagic activity in different tissues, such as liver and muscle, but much less is...
Nov 1, 2016
Hrynevich SV, Waseem TV, Hébert A, Pellerin L, Fedorovich SV
The ketogenic diet is used as a prophylactic treatment for different types of brain diseases, such as epilepsy or Alzheimer's disease. In such a diet, carbohydrates are replaced by fats in everyday food, resulting in a...
Nov 1, 2016
Ni H, Zhao DJ, Tian T
Because the ketogenic diet (KD) was affecting expression of energy metabolism- related genes in hippocampus and because lipid membrane peroxidation and its associated autophagy stress were also found to be involved in ...
Nov 1, 2016
Yeo C, Tan VH, Wong KC
CLINICAL INTRODUCTION: A 22-year-old man was referred to us for syncope during a game of Captain's ball. There was no prodrome. His friends did not notice any ictal movements. He was otherwise well prior to passing out...
Oct 27, 2016
Nair DR
PURPOSE OF REVIEW: This review discusses the definition, evaluation, and management of patients with drug-resistant epilepsy. RECENT FINDINGS: Drug-resistant epilepsy is defined as a failure of two or more appr...
Oct 27, 2016
Reif PS, Tsai MH, Helbig I, Rosenow F, Klein KM
INTRODUCTION: Therapy with current antiepileptic drugs aims at reducing the likelihood of seizure occurrence rather than influencing the underlying disease process. Therefore, antiepileptic drugs have an anticonvulsant...
Oct 26, 2016
Wykes RC, Kullmann DM, Pavlov I, Magloire V
BACKGROUND: Novel treatments for drug-resistant epilepsy are required. NEW METHOD: Optogenetics is a combination of optical and genetic methods used to control the activity of specific populations of excitable ...

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