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Jun 24, 2014
Vaccarezza MM, Toma MV, Ramos Guevara JD, Diez CG, Agosta GE
The modified Atkins diet (MAD) is an alternative therapeutic diet for the treatment of drug-resistant epilepsy. It consists of a diet with 60% energy from fat, 30% from protein, and 10% from carbohydrates. The objectiv...
Jun 20, 2014
Tripathi M, Kaul B
Jun 19, 2014
Mantis JG, Meidenbauer JJ, Zimick NC, Centeno NA, Seyfried TN
The ketogenic diet (KD) is known to be anticonvulsant and anti-epileptogenic. While the mechanism behind this therapeutic benefit is unclear, a reduction of circulating glucose levels through calorie restriction (CR) h...
Jun 16, 2014
Paley EL, Perry G, Sokolova O
Neurodegeneration is induced by tryptamine, a human diet constituent, which easily crosses the blood/brain barrier. Tryptamine neurotoxicity, caused by tryptophanyl-tRNA synthetase (TrpRS) inhibition and downregulation...
Jun 16, 2014
Brownlow ML, Benner L, D'Agostino D, Gordon MN, Morgan D
Dietary manipulations are increasingly viewed as possible approaches to treating neurodegenerative diseases. Previous studies suggest that Alzheimer's disease (AD) patients present an energy imbalance with brain hypome...
Jun 14, 2014
Reid CA, Mullen S, Kim TH, Petrou S
Metabolic dysfunction leading to epilepsy is well recognised. Dietary therapy, in particular the ketogenic diet, is now considered an effective option. Recent genetic studies have highlighted the central role metabolis...
Jun 11, 2014
Imai K, Ishihara E, Ikeda H
Reappraisal of ketogenic diets (KD) were delayed in Japan compared to USA and Korea. The reasons are unknown, but possible explanations are (1) Japanese food culture prefers rice and less fat and (2) ACTH therapy is pr...
Jun 10, 2014
Li HF, Zou Y, Ding G
OBJECTIVE: To systematically evaluate therapeutic success of the ketogenic diet (KD) as a treatment option for epilepsy. METHODS: Using MEDLINE and Google Scholar search, we searched for studies investigating t...
Jun 5, 2014
Hughes SD, Kanabus M, Anderson G, Hargreaves IP, Rutherford T, O'Donnell M, Cross JH, Rahman S, Eaton S, Heales SJ
The Ketogenic diet (KD) is an effective treatment with regards to treating pharmaco-resistant epilepsy. However, there are difficulties around compliance and tolerability. Consequently, there is a need for refined/simp...
Jun 4, 2014
Posar A, Santucci M
The glucose transport protein type 1 (GLUT1) deficit causes a chronic brain energy failure. The classic phenotype of GLUT1 deficiency syndrome is characterized by: Mild to severe motor delay and mental retardation; inf...