Back to Topics Listing
Jun 14, 2014
Reid CA, Mullen S, Kim TH, Petrou S
Metabolic dysfunction leading to epilepsy is well recognised. Dietary therapy, in particular the ketogenic diet, is now considered an effective option. Recent genetic studies have highlighted the central role metabolis...
Jun 11, 2014
Imai K, Ishihara E, Ikeda H
Reappraisal of ketogenic diets (KD) were delayed in Japan compared to USA and Korea. The reasons are unknown, but possible explanations are (1) Japanese food culture prefers rice and less fat and (2) ACTH therapy is pr...
Jun 10, 2014
Li HF, Zou Y, Ding G
OBJECTIVE: To systematically evaluate therapeutic success of the ketogenic diet (KD) as a treatment option for epilepsy. METHODS: Using MEDLINE and Google Scholar search, we searched for studies investigating t...
Jun 5, 2014
Hughes SD, Kanabus M, Anderson G, Hargreaves IP, Rutherford T, O'Donnell M, Cross JH, Rahman S, Eaton S, Heales SJ
The Ketogenic diet (KD) is an effective treatment with regards to treating pharmaco-resistant epilepsy. However, there are difficulties around compliance and tolerability. Consequently, there is a need for refined/simp...
Jun 4, 2014
Posar A, Santucci M
The glucose transport protein type 1 (GLUT1) deficit causes a chronic brain energy failure. The classic phenotype of GLUT1 deficiency syndrome is characterized by: Mild to severe motor delay and mental retardation; inf...
Jun 4, 2014
Ragona F, Matricardi S, Castellotti B, Patrini M, Freri E, Binelli S, Granata T
We report a 12-year-old female patient with a mild phenotype of glucose transporter type 1 deficiency syndrome (Glut1D). The clinical picture was characterized by refractory absence epilepsy, migraine, and learning dis...
Jun 3, 2014
El-Rashidy OF, Nassar MF, Abdel-Hamid IA, Shatla RH, Abdel-Hamid MH, Gabr SS, Mohamed SG, El-Sayed WS, Shaaban SY
OBJECTIVES: The study was designed to evaluate the efficacy, safety, and tolerability of the ketogenic diet (KD) whether classic 4:1 formula or the modified Atkins diet (MAD) in intractable childhood epilepsy. ...
Jun 3, 2014
Kobow K, Kaspi A, Harikrishnan KN, Kiese K, Ziemann M, Khurana I, Fritzsche I, Hauke J, Hahnen E, Coras R, Mühlebner A, El-Osta A, Blümcke I
Epilepsy is a frequent neurological disorder, although onset and progression of seizures remain difficult to predict in affected patients, irrespective of their epileptogenic condition. Previous studies in animal model...
May 31, 2014
Byrns CN, Pitts MW, Gilman CA, Hashimoto AC, Berry MJ
Selenoproteins are a unique family of proteins, characterized by the co-translational incorporation of selenium as selenocysteine, which play key roles in antioxidant defense. Among selenoproteins, selenoprotein P (Sep...
May 27, 2014
Selter JH, Turner Z, Doerrer SC, Kossoff EH
Unlike anticonvulsant drugs and vagus nerve stimulation, there are no guidelines regarding adjustments to ketogenic diet regimens to improve seizure efficacy once the diet has been started. A retrospective chart review...