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Apr 15, 2015
Mikkelsen KH, Seifert T, Secher NH, Grøndal T, van Hall G
CONTEXT: Ketone bodies are substrates during fasting and when on a ketogenic diet not the least for the brain and implicated in the management of epileptic seizures and dementia. Moreover, D-β-hydroxybutyrate (HOB) is ...
Apr 15, 2015
Paoli A, Bianco A, Damiani E, Bosco G
An increasing number of data demonstrate the utility of ketogenic diets in a variety of metabolic diseases as obesity, metabolic syndrome, and diabetes. In regard to neurological disorders, ketogenic diet is recognized...
Apr 15, 2015
Sen S, Keough K, Gibson J
Intractable epilepsy is a common diagnosis among child neurology practitioners with medical management remaining unsatisfactory in many cases. GLUT1 deficiency syndrome (GLUT1-DS) is a disorder that should be considere...
Apr 14, 2015
Axelson HW, Isberg M, Flink R, Amandusson A
BACKGROUND: Trigeminal nerve stimulation (TNS) has recently emerged as a new therapeutic option for patients with drug-resistant epilepsy but its potential mechanisms of action are not known. Since other antiepileptic ...
Apr 14, 2015
Pablos-Sánchez T, Oliveros-Leal L, Núñez-Enamorado N, Camacho-Salas A, Moreno-Villares JM, Simón-De las Heras R
INTRODUCTION: Between 23% and 25% of epileptic children are refractory to antiepileptic drugs. In recent times there has been a renewed interest in the ketogenic diet as treatment in these patients who are not candidat...
Apr 11, 2015
Liu J, Fedinec AL, Leffler CW, Parfenova H
Cerebral blood flow dysregulation caused by oxidative stress contributes to adverse neurologic outcome of seizures. A carbon monoxide (CO) donor CORM-A1 has antioxidant and cytoprotective properties. We investigated wh...
Apr 10, 2015
Doksöz Ö, Güzel O, Yılmaz Ü, İşgüder R, Çeleğen K, Meşe T, Uysal U
The aim of this prospective study is to investigate the effect of a 6-month-long ketogenic diet on carotid intima-media thickness, carotid artery, and aortic vascular functions. Thirty-eight drug-resistant epileptic pa...
Apr 8, 2015
Joshi K, Bhatia V
Vitamin D has an important role to play in skeletal and extraskeletal health. Inspite of being a sun rich country, India has widespread vitamin D deficiency. Vitamin D deficiency can lead to serious consequences like h...
Apr 7, 2015
Martlé V, Van Ham L, Raedt R, Vonck K, Boon P, Bhatti S
Refractory epilepsy is a common disorder both in humans and dogs and treatment protocols are difficult to optimise. In humans, different non-pharmacological treatment modalities currently available include surgery, the...
Apr 4, 2015
Sangermano M, D'Aniello R, Massa G, Albano R, Pisano P, Budetta M, Scuccimarra G, Papa E, Coppola G, Vajro P
BACKGROUND AND AIMS: Several neuromotor disorders share exclusive, although often overlooked, nutritional problems. The objective of this study is therefore to delineate the frequency of malnutrition, evaluate the effe...