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Aug 14, 2015
Socała K, Nieoczym D, Pieróg M, Wlaź P
Although several studies have reported the acute anticonvulsant activity of caprylic acid in animal seizure models, little is known about the mechanism underlying this effect. Recently, the role of adenosine in the eff...
Aug 14, 2015
Erbguth F, Himmerich H
"Healthy" diets and supplements are widely used for prevention and disease modification in vascular, inflammatory and degenerative neurological diseases. Apart from a large number of cross-sectional and prospective coh...
Aug 14, 2015
Wlaź P, Socała K, Nieoczym D, Żarnowski T, Żarnowska I, Czuczwar SJ, Gasior M
Capric acid (CA10) is a 10-carbon medium-chain fatty acid abundant in the medium-chain triglyceride ketogenic diet (MCT KD). The purpose of this study was to characterize acute anticonvulsant effects of CA10 across sev...
Aug 13, 2015
Gumus H, Bayram AK, Kardas F, Canpolat M, Çağlayan AO, Kumandas S, Kendirci M, Per H
Objectives The purpose of this study was to characterize patients who were diagnosed with glucose transporter protein 1 deficiency syndrome (Glut1D), and also to assess the efficacy of ketogenic diet (KD) therapy on se...
Aug 13, 2015
Rasic-Markovic A, Rankov-Petrovic B, Hrncic D, Krstic D, Colovic M, Macut Dj, Djuric D, Stanojlovic O
Influence of folic acid on the CNS is still unclear. Folate has a neuroprotective effect, while on the other hand excess folate can exacerbate seizures in epileptics. The aim of the present study was to examine the eff...
Aug 11, 2015
Lusardi TA, Akula KK, Coffman SQ, Ruskin D, Masino SA, Boison D
Epilepsy is a highly prevalent seizure disorder which tends to progress in severity and become refractory to treatment. Yet no therapy is proven to halt disease progression or to prevent the development of epilepsy. Be...
Aug 8, 2015
Selkälä EM, Nair RR, Schmitz W, Kvist AP, Baes M, Hiltunen JK, Autio KJ
α-Methylacyl-CoA racemase (Amacr) catalyzes the racemization of the 25-methyl group in C27-intermediates in bile acid synthesis and in methyl-branched fatty acids such as pristanic acid, a metabolite derived from phyto...
Aug 5, 2015
Caraballo RH, Flesler S, Armeno M, Fortini S, Agustinho A, Mestre G, Cresta A, Buompadre MC, Escobal N
UNLABELLED: The ketogenic diet (KD) has been used as an alternative treatment for patients with refractory status epilepticus (SE). PURPOSE: In this retrospective study we assess the efficacy and tolerability o...
Aug 5, 2015
Hirano Y, Oguni H, Shiota M, Nishikawa A, Osawa M
PURPOSE: Ketogenic diet therapy (KD) has been used to treat children with refractory generalized epilepsy. We herein reported the efficacy of KD for West syndrome (WS) resistant to ACTH therapy. SUBJECTS: SUBJE...
Aug 5, 2015
Shirobokov V, Yankovskii D, Dyment G
The review is devoted to the issues of using smectites in medicine. Modern information concerning smectite composition, structure, physico-chemical properties and reasonability of using them with health-improving purpo...

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