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May 1, 2016
Çavuş I, Romanyshyn JC, Kennard JT, Farooque P, Williamson A, Eid T, Spencer SS, Duckrow R, Dziura J, Spencer DD
OBJECTIVE: Aberrant glutamate and γ-aminobutyric acid (GABA) neurotransmission contribute to seizure generation and the epileptic state. However, whether levels of these neurochemicals are abnormal in epileptic patient...
Apr 30, 2016
Asadi-Pooya AA, Sperling MR
PURPOSE: To evaluate the demographic and clinical manifestations and postsurgical outcome of childhood-onset mesial temporal sclerosis and temporal lobe epilepsy (MTS-TLE) and establishing the potential differences as ...
Apr 30, 2016
Fang Y, Wang X
Status epilepticus (SE) is an acute and severe illness of the central nervous system, and prolonged SE can lead to brain damage and even death. Ketamine is a noncompetitive antagonist of glutamatergic N-methyl-d-aspart...
Apr 30, 2016
Begley CE, Durgin TL
OBJECTIVE: To develop estimates of the direct cost of epilepsy in the United States for the general epilepsy population and sub-populations by systematically comparing similarities and differences in types of estimates...
Apr 30, 2016
Wincent J, Kolbjer S, Martin D, Luthman A, Åmark P, Dahlin M, Anderlid BM
Brain malformations are a major cause of therapy-refractory epilepsy as well as neurological and developmental disabilities in children. This study examined the frequency and the nature of copy number variations among ...
Apr 30, 2016
John N, Theilmann W, Frieling H, Krauss JK, Alam M, Schwabe K, Brandt C
In patients with medical-refractory schizophrenia electroconvulsive therapy (ECT), i.e., the induction of therapeutic seizures via cortical surface electrodes, is effectively used. Electroconvulsive stimulation (ECS) i...
Apr 29, 2016
Ali R, Khan MA, Siddiqui N
Epilepsy is a serious brain condition characterized by recurring seizures. It affects millions of people across the globe. Much advancement in the past has improved the understanding of the underlying pathophysiology a...
Apr 28, 2016
Falco-Walter JJ, Bleck T
Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While...
Apr 28, 2016
Alapirtti T, Jylhävä J, Raitanen J, Mäkinen R, Peltola J, Hurme MA, Liimatainen S
OBJECTIVE: Cell-free DNA (cf-DNA) is a marker of inflammation and cell death. The purpose of the present study was to analyze the role of cf-DNA as a putative biomarker in refractory epilepsy. METHODS: Baseline...
Apr 27, 2016
Komaragiri A, Detyniecki K, Hirsch LJ
Epilepsy is widely prevalent globally and has emerged as a well-studied neurological condition in the recent past. Seizure clusters, a type of seizures, and several aspects pertaining to the etiopathogenesis and manage...

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