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Dec 9, 2016
Zelano C, Jiang H, Zhou G, Arora N, Schuele S, Rosenow J, Gottfried JA
The need to breathe links the mammalian olfactory system inextricably to the respiratory rhythms that draw air through the nose. In rodents and other small animals, slow oscillations of local field potential activity a...
Dec 6, 2016
Suzuki K, Kawataki T, Sato H, Ogiwara M, Kinouchi H
The number of patients who suffer from symptomatic partial epilepsy is significant, and those who undergo neurosurgery often experience refractory seizures. Levetiracetam (LEV) is a new-generation anti epileptic drug (...
Dec 5, 2016
Kurth C, Kockelmann E, Steinhoff BJ
PURPOSE: Perampanel (PER) and lacosamide (LCM) are antiepileptic drugs (AEDs) approved for the adjunctive treatment of partial-onset seizures. At the time of market entry, information on clinical effectiveness of new A...
Dec 2, 2016
Amtul Z, Aziz AA
Epilepsy is characterized by the hyperexcitability of various neuronal circuits that results due to the imbalance between glutamate-mediated excitation of voltage-gated cation channels and γ-amino butyric acid (GABA)-m...
Dec 2, 2016
Liu X, Ou S, Xu T, Liu S, Yuan J, Huang H, Qin L, Yang H, Chen L, Tan X, Chen Y
Epigenetics underlying refractory epilepsy is poorly understood, especially in patients without distinctive genetic alterations. DNA methylation may affect gene expression in epilepsy without affecting DNA sequences. H...
Nov 30, 2016
Lee CY, Lim SN, Wu T, Lee ST
BACKGROUND: Refractory status epilepticus(RSE) is considered a medical emergency in neurology and is related to a high mortality rate. We report a successfully treated case of RSE using deep brain stimulation (DBS) at ...
Nov 29, 2016
Trinka E, Kälviäinen R
PURPOSE: Status epilepticus (SE) requires not only urgent symptomatic treatment with antiepileptic drugs but also rapid identification and treatment of its cause. This narrative review summarizes the most important adv...
Nov 27, 2016
Shah E, Reuber M, Goulding P, Flynn C, Delanty N, Kemp S
PURPOSE: To derive clinically useful information about the efficacy and tolerability of adjunctive treatment with perampanel for refractory epilepsy in an outpatient setting. METHOD: We pooled retrospective cas...
Nov 26, 2016
Eid T, Gruenbaum SE, Dhaher R, Lee TW, Zhou Y, Danbolt NC
Epilepsy is a complex, multifactorial disease characterized by spontaneous recurrent seizures and an increased incidence of comorbid conditions such as anxiety, depression, cognitive dysfunction, and sudden unexpected ...
Nov 25, 2016
Zhang B, Wang L
A male 46 year-old patient was admitted to the Emergency Intensive Care Unit of Qinghai Provincial People's Hospital (Xining, China) in December 2008 with complaints of a headache and fever that had lasted for three da...

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