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Apr 26, 2015
Wong M, Roper SN
Malformations of cortical development constitute a variety of pathological brain abnormalities that commonly cause severe, medically-refractory epilepsy, including focal lesions, such as focal cortical dysplasia, heter...
Apr 25, 2015
Betjemann JP, Lowenstein DH
Status epilepticus is a common neurological emergency with considerable associated health-care costs, morbidity, and mortality. The definition of status epilepticus as a prolonged seizure or a series of seizures with i...
Apr 25, 2015
Funck VR, Ribeiro LR, Pereira LM, de Oliveira CV, Grigoletto J, Della-Pace ID, Fighera MR, Royes LF, Furian AF, Larrick JW, Oliveira MS
Epilepsy is a life-shortening brain disorder affecting approximately 1% of the worldwide population. Most epilepsy patients are refractory to currently available antiepileptic drugs (AEDs). Knowledge about the mechanis...
Apr 25, 2015
Błaszczyk B
Tiagabine belongs to a new generation of antiepileptic drugs with a unique mechanism of action. It is well-absorbable from the gastrointestinal tract, has a linear pharmacokinetics, does not affect cognitive function a...
Apr 24, 2015
Rocamora R, Becerra JL, Fossas P, Gomez M, Vivanco-Hidalgo RM, Mauri JA, Molins A
PURPOSE: Ictal piloerection is an infrequent seizure semiology that is commonly overlooked as an ictal epileptic manifestation. Piloerection is considered to be principally caused by temporal lobe activity although fro...
Apr 24, 2015
Zelano J, Möller F, Dobesberger J, Trinka E, Kumlien E
PURPOSE: Status epilepticus (SE) has attracted renewed interest lately, and efforts are made to optimize every treatment stage. For refractory SE, optimal supporting care involves mechanical ventilation and intensive c...
Apr 22, 2015
Lee DJ, Zwienenberg-Lee M, Seyal M, Shahlaie K
OBJECT: Accurate placement of intracranial depth and subdural electrodes is important in evaluating patients with medically refractory epilepsy for possible resection. Confirming electrode locations on postoperative CT...
Apr 22, 2015
Na M, Liu Y, Shi C, Gao W, Ge H, Wang Y, Wang H, Long Y, Shen H, Shi C, Lin Z
PURPOSE: Hippocampal sclerosis (HS), the most common feature of mesial temporal lobe epilepsy (MTLE), is widely accepted as surgical indication for refractory epilepsy. Pathological hallmarks in hippocampal dentate gyr...
Apr 22, 2015
Marchi LR, Seraphim EA, Corso JT, Naves PV, Carvalho KC, Ramirez MD, Ferrari-Marinho T, Guaranha MS, Yacubian EM
Epileptic spasms were defined by the International League Against Epilepsy Task Force on Classification and Terminology in 2001 as a specific seizure type. Epileptic spasms without hypsarrhythmia have been described in...
Apr 22, 2015
Dash D, Aggarwal V, Joshi R, Padma MV, Tripathi M
PURPOSE: The present study was conducted with the aim of evaluating the effects of reducing the number of antiepileptic drugs (AEDs) administered to patients with drug-refractory epilepsy (DRE) during their admission a...

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