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Nov 16, 2016
Wormuth C, Lundt A, Henseler C, Müller R, Broich K, Papazoglou A, Weiergräber M
BACKGROUND: Researchers have gained substantial insight into mechanisms of synaptic transmission, hyperexcitability, excitotoxicity and neurodegeneration within the last decades. Voltage-gated Ca(2+) channels are of ce...
Nov 15, 2016
Papazoglou A, Soos J, Lundt A, Wormuth C, Ginde VR, Müller R, Henseler C, Broich K, Xie K, Ehninger D, Haenisch B, Weiergräber M
Alzheimer's disease (AD) is a multifactorial disorder leading to progressive memory loss and eventually death. In this study an APPswePS1dE9 AD mouse model has been analyzed using implantable video-EEG radiotelemetry t...
Nov 5, 2016
Zheng Y, Wang G, Wang J
Objective This study aims to verify whether the simple threshold-crossing method can work well enough to achieve the realistic application of seizure prediction on the basis of a large public database, and examines how...
Oct 26, 2016
Lundt A, Wormuth C, Siwek ME, Müller R, Ehninger D, Henseler C, Broich K, Papazoglou A, Weiergräber M
EEG radiotelemetry plays an important role in the neurological characterization of transgenic mouse models of neuropsychiatric and neurodegenerative diseases as well as epilepsies providing valuable insights into under...
Jan 23, 2016
Tzadok M, Uliel-Siboni S, Linder I, Kramer U, Epstein O, Menascu S, Nissenkorn A, Yosef OB, Hyman E, Granot D, Dor M, Lerman-Sagie T, Ben-Zeev B
PURPOSE: To describe the experience of five Israeli pediatric epilepsy clinics treating children and adolescents diagnosed as having intractable epilepsy with a regimen of medical cannabis oil. METHODS: A retro...
Nov 5, 2015
Siwek ME, Müller R, Henseler C, Trog A, Lundt A, Wormuth C, Broich K, Ehninger D, Weiergräber M, Papazoglou A
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by impairment of memory function. The 5XFAD mouse model was analyzed and compared with wild-type (WT) controls for aberrant cortical e...
Nov 5, 2015
Paesler K, Xie K, Hettich MM, Siwek ME, Ryan DP, Schröder S, Papazoglou A, Broich K, Müller R, Trog A, Garthe A, Kempermann G, Weiergräber M, Ehninger D
Alzheimer's disease (AD) has been associated with increased phosphorylation of the translation initiation factor 2α (eIF2α) at serine 51. Increased phosphorylation of eIF2α alters translational control and may thereby ...
Sep 12, 2015
Sandler RA, Song D, Hampson RE, Deadwyler SA, Berger TW, Marmarelis VZ
OBJECTIVE: Traditional hippocampal modeling has focused on the series of feedforward synapses known as the trisynaptic pathway. However, feedback connections from CA1 back to the hippocampus through the entorhinal cor...
Sep 12, 2015
Weiergräber M, Papazoglou A
Sep 1, 2015
Hoffman FA
Botanicals are ingredients that can be marketed as foods, drugs, cosmetics, and medical devices in the United States. When a botanical is intended to diagnose, treat, prevent, mitigate, or cure a disease, it is conside...

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