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Nov 29, 2015
Morrell MJ, Halpern C
Closed-loop, responsive focal brain stimulation provides a new treatment option for patients with refractory partial onset seizures who are not good candidates for potentially curative epilepsy surgery. The first respo...
Nov 5, 2015
Siwek ME, Müller R, Henseler C, Trog A, Lundt A, Wormuth C, Broich K, Ehninger D, Weiergräber M, Papazoglou A
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by impairment of memory function. The 5XFAD mouse model was analyzed and compared with wild-type (WT) controls for aberrant cortical e...
Nov 5, 2015
Paesler K, Xie K, Hettich MM, Siwek ME, Ryan DP, Schröder S, Papazoglou A, Broich K, Müller R, Trog A, Garthe A, Kempermann G, Weiergräber M, Ehninger D
Alzheimer's disease (AD) has been associated with increased phosphorylation of the translation initiation factor 2α (eIF2α) at serine 51. Increased phosphorylation of eIF2α alters translational control and may thereby ...
Oct 27, 2015
Wu JY, Peters JM, Goyal M, Krueger D, Sahin M, Northrup H, Au KS, Cutter G, Bebin EM
BACKGROUND: We assessed the clinical utility of routine electroencephalography (EEG) in the prediction of epilepsy onset in asymptomatic infants with tuberous sclerosis complex. METHODS: This multicenter prospe...
Sep 26, 2015
Michihata N, Matsui H, Fushimi K, Yasunaga H
PURPOSE: Pediatricians generally need to treat adult patients who require long-term care for pediatric diseases. However, little is known about the characteristics of adult patients in pediatric wards. Using a national...
Sep 12, 2015
Sandler RA, Song D, Hampson RE, Deadwyler SA, Berger TW, Marmarelis VZ
OBJECTIVE: Traditional hippocampal modeling has focused on the series of feedforward synapses known as the trisynaptic pathway. However, feedback connections from CA1 back to the hippocampus through the entorhinal cor...
Sep 12, 2015
Weiergräber M, Papazoglou A
Sep 1, 2015
Hoffman FA
Botanicals are ingredients that can be marketed as foods, drugs, cosmetics, and medical devices in the United States. When a botanical is intended to diagnose, treat, prevent, mitigate, or cure a disease, it is conside...
Aug 20, 2015
Godlevsky LS, Muratova TN, Kresyun NV, van Luijtelaar G, Coenen AM
Anxiety and depression are component of interictal behavioral deteriorations that occur as a consequence of kindling, a procedure to induce chronic epilepsy. The aim of this study was to evaluate the possible effects o...
Jun 10, 2015
Zheng Y, Wang G, Wang J
OBJECTIVE: This study aims to verify whether the simple threshold-crossing method can work well enough to achieve the realistic application of seizure prediction on the basis of a large public database, and examines h...