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Jan 24, 2017
Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS, Koepp MJ
The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII) took place in Madrid, Spain from June 26th to 29th 2016. For the first time, the last day of the conference focused solely on new medi...
Dec 19, 2016
Weiergräber M
Dec 15, 2016
Tzadok M, Uliel-Siboni S, Linder I, Kramer U, Epstein O, Menascu S, Nissenkorn A, Yosef OB, Hyman E, Granot D, Dor M, Lerman-Sagie T, Ben-Zeev B
PURPOSE: To describe the experience of five Israeli pediatric epilepsy clinics treating children and adolescents diagnosed as having intractable epilepsy with a regimen of medical cannabis oil. METHODS: A retro...
Nov 16, 2016
Wormuth C, Lundt A, Henseler C, Müller R, Broich K, Papazoglou A, Weiergräber M
BACKGROUND: Researchers have gained substantial insight into mechanisms of synaptic transmission, hyperexcitability, excitotoxicity and neurodegeneration within the last decades. Voltage-gated Ca(2+) channels are of ce...
Nov 15, 2016
Papazoglou A, Soos J, Lundt A, Wormuth C, Ginde VR, Müller R, Henseler C, Broich K, Xie K, Ehninger D, Haenisch B, Weiergräber M
Alzheimer's disease (AD) is a multifactorial disorder leading to progressive memory loss and eventually death. In this study an APPswePS1dE9 AD mouse model has been analyzed using implantable video-EEG radiotelemetry t...
Nov 5, 2016
Zheng Y, Wang G, Wang J
Objective This study aims to verify whether the simple threshold-crossing method can work well enough to achieve the realistic application of seizure prediction on the basis of a large public database, and examines how...
Oct 26, 2016
Lundt A, Wormuth C, Siwek ME, Müller R, Ehninger D, Henseler C, Broich K, Papazoglou A, Weiergräber M
EEG radiotelemetry plays an important role in the neurological characterization of transgenic mouse models of neuropsychiatric and neurodegenerative diseases as well as epilepsies providing valuable insights into under...
Nov 5, 2015
Siwek ME, Müller R, Henseler C, Trog A, Lundt A, Wormuth C, Broich K, Ehninger D, Weiergräber M, Papazoglou A
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by impairment of memory function. The 5XFAD mouse model was analyzed and compared with wild-type (WT) controls for aberrant cortical e...
Nov 5, 2015
Paesler K, Xie K, Hettich MM, Siwek ME, Ryan DP, Schröder S, Papazoglou A, Broich K, Müller R, Trog A, Garthe A, Kempermann G, Weiergräber M, Ehninger D
Alzheimer's disease (AD) has been associated with increased phosphorylation of the translation initiation factor 2α (eIF2α) at serine 51. Increased phosphorylation of eIF2α alters translational control and may thereby ...
Sep 12, 2015
Sandler RA, Song D, Hampson RE, Deadwyler SA, Berger TW, Marmarelis VZ
OBJECTIVE: Traditional hippocampal modeling has focused on the series of feedforward synapses known as the trisynaptic pathway. However, feedback connections from CA1 back to the hippocampus through the entorhinal cor...

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