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Link: https://www.ncbi.nlm.nih.gov/pubmed/28704741?dopt=Abstract
Jul 14, 2017
Outside the box: Medications worth considering when traditional antiepileptic drugs have failed.
Turner AL, Perry MS
PURPOSE: Review and discuss medications efficacious for seizure control, despite primary indications for other diseases, as treatment options in patients who have failed therapy with traditional antiepileptic drugs (AE...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28703446?dopt=Abstract
Jul 14, 2017
Paroxysmal Dyskinesia in Border Terriers: Clinical, Epidemiological, and Genetic Investigations.
Stassen QEM, Koskinen LLE, van Steenbeek FG, Seppälä EH, Jokinen TS, Prins PGM, Bok HGJ, Zandvliet MMJM, Vos-Loohuis M, Leegwater PAJ, Lohi H
BACKGROUND: In the last decade, a disorder characterized by episodes of involuntary movements and dystonia has been recognized in Border Terriers. OBJECTIVES: To define clinical features of paroxysmal dyskinesi...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28702868?dopt=Abstract
Jul 14, 2017
Safety and tolerability of the ketogenic diet used for the treatment of refractory childhood epilepsy: a systematic review of published prospective studies.
Cai QY, Zhou ZJ, Luo R, Gan J, Li SP, Mu DZ, Wan CM
BACKGROUND: To review the available evidence from prospective studies on the safety and tolerability of the ketogenic diet (KD) for the treatment of refractory childhood epilepsy. METHODS: A comprehensive bibli...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28701250?dopt=Abstract
Jul 14, 2017
The Ketogenic Diet: Making a Comeback.
Walczyk T, Wick JY
Americans have embraced a large number of diets in an attempt to manage obesity, improve quality of life, and address specific health problems. Among diets developed to address health problems, the ketogenic diet has h...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28694620?dopt=Abstract
Jul 12, 2017
Nonalcoholic Wernicke's Encephalopathy: A Retrospective Study from a Tertiary Care Center in Northern India.
Shah IA, Asimi RP, Kawoos Y, Wani M, Saleem T, Baba WN
OBJECTIVE: The objective of this study was to describe the demographic features, clinical presentation, and management and outcome of fifty cases of nonalcoholic Wernicke's encephalopathy from a tertiary care hospital ...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28687854?dopt=Abstract
Jul 9, 2017
Neuroprotective effects of vitamin D alone or in combination with lamotrigine against lithium-pilocarpine model of status epilepticus in rats.
Mahfoz AM, Abdel-Wahab AF, Afify MA, Shahzad N, Ibrahim IAA, ElSawy NA, Bamagous GA, Al Ghamdi SS
Status epilepticus (SE) is considered one of the major serious forms of epilepsy with high mortality rate. Since the currently available antiepileptic drugs have low efficacy and high adverse effects, new more efficien...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28687765?dopt=Abstract
Jul 9, 2017
Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters.
Forero-Quintero LS, Deitmer JW, Becker HM
Epilepsy is a chronic neurological disorder that affects approximately 50 million people worldwide. Ketogenic diet (KD) can be a very effective treatment for intractable epilepsy. Potential mechanisms of action for KD ...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28682459?dopt=Abstract
Jul 7, 2017
Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet.
Khabbush A, Orford M, Tsai YC, Rutherford T, O'Donnell M, Eaton S, Heales SJR
OBJECTIVE: The medium-chain triglyceride (MCT) ketogenic diet contains both octanoic (C8) and decanoic (C10) acids. The diet is an effective treatment for pharmacoresistant epilepsy. Although the exact mechanism for it...
Link: https://www.ncbi.nlm.nih.gov/pubmed/27781560?dopt=Abstract
Jul 6, 2017
Precision medicine in genetic epilepsies: break of dawn?
Reif PS, Tsai MH, Helbig I, Rosenow F, Klein KM
INTRODUCTION: Therapy with current antiepileptic drugs aims at reducing the likelihood of seizure occurrence rather than influencing the underlying disease process. Therefore, antiepileptic drugs have an anticonvulsant...
Link: https://www.ncbi.nlm.nih.gov/pubmed/28675558?dopt=Abstract
Jul 5, 2017
Clinical studies and anti-inflammatory mechanisms of treatments.
French JA, Koepp M, Naegelin Y, Vigevano F, Auvin S, Rho JM, Rosenberg E, Devinsky O, Olofsson PS, Dichter MA
In this exciting era, we are coming closer and closer to bringing an anti-inflammatory therapy to the clinic for the purpose of seizure prevention, modification, and/or suppression. At present, it is unclear what this ...

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