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Apr 18, 2015
Saade D, Joshi C
BACKGROUND: Malignant migrating partial seizures in infancy is a devastating pharmacoresistent epileptic encephalopathy of unknown etiology characterized by onset in the first 6 months of life, continuous migrating foc...
Apr 17, 2015
Larsen JA, Owens TJ, Fascetti AJ
Apr 16, 2015
Martinelli D, Diodato D, Ponzi E, Monné M, Boenzi S, Bertini E, Fiermonte G, Dionisi-Vici C
BACKGROUND: Hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome is a rare autosomal recessive disorder of the urea cycle. HHH has a panethnic distribution, with a major prevalence in Canada, Italy and Jap...
Apr 15, 2015
Mikkelsen KH, Seifert T, Secher NH, Grøndal T, van Hall G
CONTEXT: Ketone bodies are substrates during fasting and when on a ketogenic diet not the least for the brain and implicated in the management of epileptic seizures and dementia. Moreover, D-β-hydroxybutyrate (HOB) is ...
Apr 15, 2015
Paoli A, Bianco A, Damiani E, Bosco G
An increasing number of data demonstrate the utility of ketogenic diets in a variety of metabolic diseases as obesity, metabolic syndrome, and diabetes. In regard to neurological disorders, ketogenic diet is recognized...
Apr 15, 2015
Sen S, Keough K, Gibson J
Intractable epilepsy is a common diagnosis among child neurology practitioners with medical management remaining unsatisfactory in many cases. GLUT1 deficiency syndrome (GLUT1-DS) is a disorder that should be considere...
Apr 14, 2015
Axelson HW, Isberg M, Flink R, Amandusson A
BACKGROUND: Trigeminal nerve stimulation (TNS) has recently emerged as a new therapeutic option for patients with drug-resistant epilepsy but its potential mechanisms of action are not known. Since other antiepileptic ...
Apr 14, 2015
Pablos-Sánchez T, Oliveros-Leal L, Núñez-Enamorado N, Camacho-Salas A, Moreno-Villares JM, Simón-De las Heras R
INTRODUCTION: Between 23% and 25% of epileptic children are refractory to antiepileptic drugs. In recent times there has been a renewed interest in the ketogenic diet as treatment in these patients who are not candidat...
Apr 11, 2015
Liu J, Fedinec AL, Leffler CW, Parfenova H
Cerebral blood flow dysregulation caused by oxidative stress contributes to adverse neurologic outcome of seizures. A carbon monoxide (CO) donor CORM-A1 has antioxidant and cytoprotective properties. We investigated wh...
Apr 10, 2015
Doksöz Ö, Güzel O, Yılmaz Ü, İşgüder R, Çeleğen K, Meşe T, Uysal U
The aim of this prospective study is to investigate the effect of a 6-month-long ketogenic diet on carotid intima-media thickness, carotid artery, and aortic vascular functions. Thirty-eight drug-resistant epileptic pa...

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