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Aug 28, 2015
Aylward NM, Shah N, Sellers EA
Initiation of the ketogenic diet in a child with epilepsy and type 1 diabetes mellitus presents a challenge because the distinction between diet-induced ketosis and diabetic ketoacidosis is difficult to discern. We rep...
Aug 28, 2015
Wu T, Li X, Ding Y, Liu Y, Song J, Wang Q, Li M, Qin Y, Yang Y
OBJECTIVE: Argininemia is a rare disorder of urea cycle defect. The clinical manifestations of this disorder are similar to those of cerebral palsy so that the diagnosis is usually much delayed. This study aimed to inv...
Aug 28, 2015
Osborn KE, Shytle RD, Frontera AT, Soble JR, Schoenberg MR
Mg2+ is an abundant mineral in the body serving many biochemical functions. Magnesium supplementation has been shown to raise seizure threshold in animal and human studies, but the etiological contribution of magnesium...
Aug 26, 2015
Selter JH, Turner Z, Doerrer SC, Kossoff EH
Unlike anticonvulsant drugs and vagus nerve stimulation, there are no guidelines regarding adjustments to ketogenic diet regimens to improve seizure efficacy once the diet has been started. A retrospective chart review...
Aug 26, 2015
Saboul C, Darteyre S, Ged C, Fichtner C, Gay C, Stephan JL
Cerebral sinovenous thrombosis is unusual during childhood and requires early and accurate management because of its detrimental consequences. We report on the case of a 2-year-old boy with mild psychomotor delay, who ...
Aug 26, 2015
Doksöz Ö, Çeleğen K, Güzel O, Yılmaz Ü, Uysal U, İşgüder R, Çeleğen M, Meşe T
OBJECTIVE: Our primary aim was to determine the short-term effects of a ketogenic diet on cardiac ventricular function in patients with refractory epilepsy. METHODS: Thirty-eight drug-resistant epileptic patien...
Aug 25, 2015
Lambrechts DA, de Kinderen RJ, Vles HS, de Louw AJ, Aldenkamp AP, Majoie MJ
The present study assessed the long-term (i.e., 24months) efficacy of the ketogenic diet (KD) as an add-on therapy in children with refractory epilepsy, with focus on seizure frequency, seizure severity, and tolerabili...
Aug 25, 2015
Kouga T, Shimbo H, Iai M, Yamashita S, Ishii A, Ihara Y, Hirose S, Yamakawa K, Osaka H
OBJECTIVE: The objective of this study was to investigate stiripentol (STP) administration in cases of Dravet syndrome (DS) by comparing CYP2C19 allelic polymorphisms with the clinical effects of STP, including plasma ...
Aug 20, 2015
Arya R, Greiner HM, Horn PS, Turner M, Holland KD, Mangano FT
PURPOSE: Corpus callosotomy and vagus nerve stimulation are common palliative options for people with drug-resistant epilepsy when resective epilepsy surgery is not feasible. Because most of the published corpus callos...
Aug 15, 2015
Dressler A, Trimmel-Schwahofer P, Reithofer E, Mühlebner A, Gröppel G, Reiter-Fink E, Benninger F, Grassl R, Feucht M
UNLABELLED: There is strong evidence for the use of the ketogenic diet (KD) in Dravet syndrome (DS). The purpose of this study was to evaluate both effectiveness and tolerability in comparison with various antiepilepti...

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