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Apr 26, 2015
Rohde NN, Baca CB, Van Cott AC, Parko KL, Amuan ME, Pugh MJ
OBJECTIVE: We examined patterns of antiepileptic drug (AED) use in a cohort of Iraq/Afghanistan war veterans (IAVs) who were previously identified as having epilepsy. We hypothesized that clinicians would be more likel...
Apr 24, 2015
Guenther S, Bauer S, Hagge M, Knake S, Olmes DG, Tackenberg B, Rosenow F, Hamer HM
PURPOSE: There is growing evidence that complex interactions between seizures and the immune system shape the course of epilepsy. However, systematic analyses of the effects of antiepileptic drugs (AED) on the immune s...
Apr 23, 2015
Krumholz A, Wiebe S, Gronseth GS, Gloss DS, Sanchez AM, Kabir AA, Liferidge AT, Martello JP, Kanner AM, Shinnar S, Hopp JL, French JA
OBJECTIVE: To provide evidence-based recommendations for treatment of adults with an unprovoked first seizure. METHODS: We defined relevant questions and systematically reviewed published studies according to t...
Apr 22, 2015
Stephen LJ, Kelly K, Parker P, Brodie MJ
PURPOSE: In 2008, lacosamide (LCM) was licensed in Europe for the adjunctive treatment of focal-onset seizures. At that time a prospective audit was initiated at the Western Infirmary to assess outcomes with this antie...
Apr 22, 2015
Vecht CJ, Kerkhof M, Duran-Pena A
Brain tumor-related epilepsy (BTE) is common in low- and high-grade gliomas. The risk of seizures varies between 60% and 100% among low-grade gliomas and between 40% and 60% in glioblastomas. The presence of seizures i...
Apr 22, 2015
Correia FD, Freitas J, Magalhães R, Lopes J, Ramalheira J, Lopes-Lima J, Chaves J
PURPOSE: Eslicarbazepine acetate (ESL) is a new generation voltage-gated sodium channel blocker. It has completed one phase II clinical trial and three phase III clinical trials, two of which with 1-year open label ext...
Apr 22, 2015
Chiang KL, Cheng CY
OBJECTIVE: Children with epilepsy may have comorbidities that result in significant disability. Epidemiological information for pediatric patients with epilepsy in Taiwan is scant. This research estimates the prevalenc...
Apr 22, 2015
Beydoun A, Sawaya MT, Alam E, Hmaimess G, Ezzeddine K, Younes F
PURPOSE: Treatment of newly diagnosed epilepsy with a single antiepileptic drug (AED) is the favored approach for seizure management. This observational study aimed to assess, under daily practice conditions, remission...
Apr 22, 2015
Lattanzi S, Cagnetti C, Foschi N, Provinciali L, Silvestrini M
PURPOSE: To evaluate the 1-year efficacy and safety of oral lacosamide as conversion monotherapy in adult patients with partial onset seizures with or without generalization. METHOD: We prospectively followed-u...
Apr 18, 2015
Ding D, Quigg M, Starke RM, Xu Z, Yen CP, Przybylowski CJ, Dodson BK, Sheehan JP
OBJECT The temporal lobe is particularly susceptible to epileptogenesis. However, the routine use of anticonvulsant therapy is not implemented in temporal lobe AVM patients without seizures at presentation. The goals o...