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Oct 24, 2014
Harden CL
PURPOSE OF REVIEW: This review encompasses issues regarding the management of women with epilepsy and pregnancy, including preconception planning, antiepileptic drug (AED) effects on the exposed offspring, and conseque...
Oct 24, 2014
Walker LE, Mirza N, Yip VL, Marson AG, Pirmohamed M
Epilepsy affects 50 million persons worldwide, a third of whom continue to experience debilitating seizures despite optimum anti-epileptic drug (AED) treatment. Twelve-month remission from seizures is less likely in fe...
Oct 23, 2014
Braun KP, Schmidt D
PURPOSE OF REVIEW: Based on the available evidence, we aim to balance risks and benefits of antiepileptic drug (AED) withdrawal in medically and surgically treated adults and children who achieved remission. We summari...
Oct 23, 2014
Kim YS, Kim DW, Jung KH, Lee ST, Kang BS, Byun JI, Yeom JS, Chu K, Lee SK
PURPOSE: Hyponatremia is one of the most common adverse effects in patients treated with oxcarbazepine (OXC). Most patients with OXC-induced hyponatremia are asymptomatic, so the presence of severe or symptomatic hypon...
Oct 22, 2014
Kibar AE, Unver O, Oflaz MB, Güven AS, Balli S, Ece I, Erdem S, Içağasıoğlu FD
Impaired cardiac myocardial function may contribute to the risk for sudden unexpected death of a patient with epilepsy. This study aimed to investigate the effect of antiepilepsy drugs (AEDs) on cardiac function in ped...
Oct 22, 2014
Mehrpour M, Shojaie M, Zamani B, Gharibzadeh S, Abbasi M
We intended to evaluate the carotid intima-media thickness (CA-IMT) as a surrogate factor for atherogenesis in epileptic patients on enzyme inducer (EI) antiepileptic drugs (AEDs) or valproate (VA). The study included ...
Oct 15, 2014
May TW, Pfäfflin M, Brandt C, Füratsch N, Schmitz B, Wandschneider B, Kretz R, Runge U, Geithner J, Karakizlis H, Rosenow F, Kerling F, Stefan H
OBJECTIVES: Due to demographic change and high incidence of epilepsy in elderly, the number of elderly with epilepsies is increasing. However, only few studies investigated the impact of epilepsy on quality of life (Qo...
Oct 15, 2014
Qiao X, Sun G, Clare JJ, Werkman TR, Wadman WJ
BACKGROUND AND PURPOSE: Voltage-activated Na(+) channels contain one distinct α-subunit. In the brain NaV 1.1, NaV 1.2, NaV 1.3 and NaV 1.6 are the four most abundantly expressed α-subunits. The antiepileptic drugs (AE...
Oct 15, 2014
Kverneland M, Taubøll E, Selmer KK, Iversen PO, Nakken KO
BACKGROUND: Modified Atkins diet is a treatment option for patients with pharmacoresistant epilepsy that is not suitable for surgery. In the last few years, we have tried dietary treatment added to antiepileptic drugs ...
Oct 13, 2014
Grosso S, Parisi P, Spalice A, Verrotti A, Balestri P
BACKGROUND: Lacosamide is effective and well-tolerated antiepileptic drug (AED) in both children and adults. AIM: This multicentric, prospective study investigates the efficacy and safety of lacosamide adjuncti...

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