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Mar 28, 2017
Liu MJ, Li JW, Shi XY, Hu LY, Zou LP
OBJECTIVE: Patients with hypoparathyroidism exhibit metabolic disorders (hypocalcemia) and brain structural abnormalities (brain calcifications). Currently, studies have determined whether antiepileptic drug (AED) trea...
Mar 28, 2017
Berei TJ, Lillyblad MP, Almquist AK
Lacosamide is a new-generation antiepileptic drug (AED) most commonly used adjunctively in the setting of partial-onset seizures refractory to traditional therapy. We describe the first case report, to our knowledge, o...
Mar 28, 2017
Jiang YL, Yuan F, Yang F, Sun XL, Yang XA, Song L, Jiang W
PURPOSE: To explore predictors for short- and long-term prognosis of newly diagnosed epilepsy. METHODS: 549 consecutive patients with newly diagnosed epilepsy were reviewed, 336 were enrolled in the study. Two-...
Mar 26, 2017
Borghs S, Thieffry S, Noack-Rink M, Dedeken P, Hong LS, Byram L, Logan J, Chan J, Kiri V
BACKGROUND: Some antiepileptic drugs (AEDs) induce expression of hepatic enzymes. This can contribute to comorbidities via interference with metabolic pathways and concomitant drug metabolization, thereby increasing th...
Mar 23, 2017
Mazhar F, Malhi SM, Simjee SU
BACKGROUND: Oxidative stress plays a key role in the pathogenesis of epilepsy and contributes in underlying epileptogenesis process. Anticonvulsant drugs targeting the oxidative stress domain of epileptogenesis may pro...
Mar 21, 2017
Losch FP, Holtkamp M, McMurray R, Lendemans D, Kockelmann E
BACKGROUND: Due to inadequate seizure control achieved with antiepileptic drug (AED) monotherapy and the considerable side effects at high required doses, patients with partial-onset seizures (POS) often require AED co...
Mar 21, 2017
Belcastro V, Pisani LR, Bellocchi S, Casiraghi P, Gorgone G, Mula M, Pisani F
To explore possible correlations among brain lesion location, development of psychiatric symptoms and the use of antiepileptic drugs (AEDs) in a population of patients with brain tumor and epilepsy. The medical records...
Mar 18, 2017
Witt JA, Helmstaedter C
Antiepileptic pharmacotherapy can have a negative or positive impact on cognition and behavior. Besides individual susceptibilities (in terms of idiosyncratic reactions), the risk of adverse drug effects largely depend...
Mar 16, 2017
Suzuki K, Kawataki T, Sato H, Ogiwara M, Kinouchi H
The number of patients who suffer from symptomatic partial epilepsy is significant, and those who undergo neurosurgery often experience refractory seizures. Levetiracetam (LEV) is a new-generation anti epileptic drug (...
Mar 16, 2017
Tosun A, Erisen Karaca S, Unuvar T, Yurekli Y, Yenisey C, Omurlu IK
PURPOSE: We aimed to evaluate the relationship between bone mineral density (BMD) disorders and possible risk factors in patients with epilepsy only (EO), cerebral palsy only (CPO), and cerebral palsy-epilepsy (CP + E)...

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