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Jul 30, 2015
Ley M, Principe A, Jiménez-Conde J, Rocamora R
INTRODUCTION: Older dibenzazepines with a carboxamide substitution have been demonstrated to cause deleterious effects on lipid metabolism profile, as well as frequent hyponatremia. The aim of our study is to assess th...
Jul 30, 2015
Ismayilova V, Demir AU, Tezer FI
OBJECTIVE: The clinically important interaction between epilepsy and sleep is complex. The aim of this paper is to review the frequency of sleep complaints and the comorbidity of sleep disorders in people with epilepsy...
Jul 29, 2015
Lerche H, Daniluk J, Lotay N, DeRossett S, Edwards S, Brandt C
PURPOSE: To assess efficacy/tolerability of ezogabine (EZG)/retigabine (RTG) in combination with specified monotherapy antiepileptic drug (AED) treatments in adults with uncontrolled partial-onset seizures using a flex...
Jul 29, 2015
Lv N, Qu J, Long H, Zhou L, Cao Y, Long L, Liu Z, Xiao B
PURPOSE: As important ion channels of the central nervous system, calcium channels not only take part in epileptogenesis but also act as the targets of commonly used antiepileptic drugs (AEDs). Thus, this study aimed t...
Jul 29, 2015
Chapman SC, Horne R, Eade R, Balestrini S, Rush J, Sisodiya SM
OBJECTIVE: Nonadherence to antiepileptic drugs (AEDs) is a common cause of poor seizure control. This study examines whether reported adherence to AEDs is related to variables identified in the National Institute for H...
Jul 28, 2015
Siniscalchi A, Scaglione F, Sanzaro E, Iemolo F, Albertini G, Quirino G, Manes MT, Gratteri S, Mercuri NB, De Sarro G, Gallelli L
BACKGROUND AND OBJECTIVES: Sudden unexplained/unexpected death (SUDEP) is related to high mortality in patients with epilepsy. The prolongation of QT interval, involved in cardiac arrhythmia-related SUDEP, may be preci...
Jul 27, 2015
Loiselle K, Rausch JR, Modi AC
OBJECTIVE: This study aimed to identify psychosocial predictors of two-year antiepileptic drug (AED) adherence trajectories among youth with newly diagnosed epilepsy, controlling for known demographic and medical facto...
Jul 24, 2015
Pisano T, Numis AL, Heavin SB, Weckhuysen S, Angriman M, Suls A, Podesta B, Thibert RL, Shapiro KA, Guerrini R, Scheffer IE, Marini C, Cilio MR
OBJECTIVES: To describe the antiepileptic drug (AED) treatment of patients with early infantile epileptic encephalopathy due to KCNQ2 mutations during the neonatal phase and the first year of life. METHODS: We ...
Jul 24, 2015
Nolan SJ, Marson AG, Weston J, Tudur Smith C
BACKGROUND: This is an updated version of the original Cochrane review published in Issue 1, 2003, of the Cochrane Database of Systematic Reviews.Epilepsy is a common neurological condition in which abnormal electrical...
Jul 23, 2015
Perucca E, Battino D, Tomson T
The purpose of this review is to discuss gender-related aspects in the, pharmacokinetics, effects, selection and use of antiepileptic drugs (AED). In general, there are few known gender related differences in pharmacok...

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