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Oct 29, 2014
Héja L
Although glial proliferation of the epileptic loci is recognized for more than a century in certain focal epilepsies, the role of astrocytes in epileptic conditions is receiving significant attention only in recent yea...
Oct 28, 2014
Escalante-Santiago D, Feria-Romero IA, Ribas-Aparicio RM, Rayo-Mares D, Fagiolino P, Vázquez M, Escamilla-Núñez C, Grijalva-Otero I, López-García MA, Orozco-Suárez S
Although the Pgp efflux transport protein is overexpressed in resected tissue of patients with epilepsy, the presence of polymorphisms in MDR1/ABCB1 and MRP2/ABCC2 in patients with antiepileptic-drugs resistant epileps...
Oct 25, 2014
Vydrova R, Kršek P, Kyncl M, Jahodova A, Dvorak J, Komarek V, Delalande O, Tichy M
A 4-year-old girl with intractable epilepsy due to left-side hemispheric cortical dysplasia underwent a hemispherotomy. She was seizure-free after the surgery. EEG showed persistent abundant epileptiform activity over ...
Oct 25, 2014
Roivainen R, Karvonen MK, Puumala T
New antiepileptic drug (AED) options for generalised seizure types have been adopted for use as treatment for Unverricht-Lundborg disease. Whether this has led to improved seizure control or functional outcome in ULD p...
Oct 25, 2014
Semah F, Thomas P, Coulbaut S, Derambure P
AIM: The aim of this study was to evaluate the impact of two different therapeutic strategies in patients with partial seizures who were intractable to the first prescribed antiepileptic drug (AED); alternative monothe...
Oct 24, 2014
Harden CL
PURPOSE OF REVIEW: This review encompasses issues regarding the management of women with epilepsy and pregnancy, including preconception planning, antiepileptic drug (AED) effects on the exposed offspring, and conseque...
Oct 24, 2014
Walker LE, Mirza N, Yip VL, Marson AG, Pirmohamed M
Epilepsy affects 50 million persons worldwide, a third of whom continue to experience debilitating seizures despite optimum anti-epileptic drug (AED) treatment. Twelve-month remission from seizures is less likely in fe...
Oct 23, 2014
Braun KP, Schmidt D
PURPOSE OF REVIEW: Based on the available evidence, we aim to balance risks and benefits of antiepileptic drug (AED) withdrawal in medically and surgically treated adults and children who achieved remission. We summari...
Oct 23, 2014
Kim YS, Kim DW, Jung KH, Lee ST, Kang BS, Byun JI, Yeom JS, Chu K, Lee SK
PURPOSE: Hyponatremia is one of the most common adverse effects in patients treated with oxcarbazepine (OXC). Most patients with OXC-induced hyponatremia are asymptomatic, so the presence of severe or symptomatic hypon...
Oct 22, 2014
Kibar AE, Unver O, Oflaz MB, Güven AS, Balli S, Ece I, Erdem S, Içağasıoğlu FD
Impaired cardiac myocardial function may contribute to the risk for sudden unexpected death of a patient with epilepsy. This study aimed to investigate the effect of antiepilepsy drugs (AEDs) on cardiac function in ped...