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Feb 7, 2016
Leong C, Mamdani MM, Gomes T, Juurlink DN, Macdonald EM, Yogendran M
OBJECTIVE: To examine the trends in antiepileptic drug (AED) use among individuals living in Manitoba with and without a history of epilepsy. METHODS: Using data obtained from administrative health databases in...
Feb 5, 2016
Gerard EE, Meador KJ
PURPOSE OF REVIEW: Caring for a woman with epilepsy requires familiarity with the implications of antiepileptic drugs (AEDs) for pregnancy and contraception as well as an understanding of the effects of female hormones...
Feb 5, 2016
Abou-Khalil BW
PURPOSE OF REVIEW: Treatment of epilepsy starts with antiepileptic drug (AED) monotherapy. Knowledge of the spectrum of efficacy, clinical pharmacology, and modes of use for individual AEDs is essential for optimal tre...
Feb 5, 2016
Hakami T, O'Brien TJ, Petty SJ, Sakellarides M, Christie J, Kantor S, Todaro M, Gorelik A, Seibel MJ, Yerra R, Wark JD
Long-term anti-epileptic drug (AED) therapy is associated with increased fracture risk. This study tested whether substituting the newer AED levetiracetam has less adverse effects on bone than older AEDs. An open-label...
Feb 4, 2016
Hookana E, Ansakorpi H, Kortelainen ML, Junttila MJ, Kaikkonen KS, Perkiömäki J, Huikuri HV
Background Epilepsy is associated with sudden death, but the reasons for this association are not well known. Objective We studied the role of antiepileptic drugs (AEDs) as a factor contributing to sudden cardiac death...
Feb 2, 2016
Devinsky O, Dilley C, Ozery-Flato M, Aharonov R, Goldschmidt Y, Rosen-Zvi M, Clark C, Fritz P
PURPOSE: A UCB-IBM collaboration explored the application of machine learning to large claims databases to construct an algorithm for antiepileptic drug (AED) choice for individual patients. METHODS: Claims dat...
Jan 29, 2016
Park YK, Eun SH, Eun BL, Byeon JH
BACKGROUND AND PURPOSE: Benign childhood epilepsy with centrotemporal spikes (BCECTS) is the most common pediatric focal epilepsy syndrome and typically has positive clinical outcomes. However, a few patients experienc...
Jan 29, 2016
Geerlings RP, Aldenkamp AP, Gottmer-Welschen LM, de With PH, Zinger S, van Staa AL, de Louw AJ
INTRODUCTION: The main goal of the transition clinic is to explore and optimize medical issues during transition from adolescence to adulthood, and to ease the transition into adult care. However, only limited data on ...
Jan 28, 2016
Borthen I
PURPOSE: Better knowledge of risk factors for women with epilepsy giving birth. METHOD: Investigating all studies reporting complications in pregnancy and deliveries in women with epilepsy during the last 15 ye...
Jan 28, 2016
Veiby G, Bjørk M, Engelsen BA, Gilhus NE
PURPOSE: The objective of this paper is to provide a synopsis of benefits and potential harmful effects of exposure to antiepileptic drugs (AEDs) via breastmilk, and present recommendations for breastfeeding in women w...

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