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Aug 29, 2014
Yeap LL, Lim KS, Lo YL, Bakar MZ, Tan CT
Hearing loss has been reported with valproic acid (VPA) use. However, this is the first case of VPA-induced hearing loss that was tested and confirmed with a VPA rechallenge, supported by serial audiometry and pharmaco...
Aug 29, 2014
Talaat FM, Kamel T, Rabah AM, Ahmed SM, El-Jaafary SI, Abdelaziz GH
Introduction: Epilepsy is a chronic disease that affects metabolism either alone or through the antiepileptic drug (AED) treatment. A risk of atherosclerosis has been found in epileptic patients. Aim: Prove the potenti...
Aug 28, 2014
AlQuliti K, Ratrout B, AlZaki A
BACKGROUND: Treatment of epilepsy with antiepileptic drugs (AED) is effective and remains the principal mode of management. A group of adverse effects and drug toxicity can develop immediately or later in the course of...
Aug 27, 2014
Onay S, Yalnızoğlu D, Topçu M, Turanlı G
The value of video-electroencephalographic monitoring (EEG-VM) in evaluating patients with epileptic disorders constitutes a major research field. This study investigates the usefulness of inpatient long-term EEG-VM fo...
Aug 27, 2014
Seven M, Batar B, Unal S, Yesil G, Yuksel A, Guven M
One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. ...
Aug 26, 2014
Yılmaz U, Yılmaz TS, Akıncı G, Korkmaz HA, Tekgül H
BACKGROUND: Limited and conflicting data exist for the influence of antiepileptic drugs on thyroid function in children. OBJECTIVE: The aim of this study was to investigate the effects of phenobarbital, valproa...
Aug 26, 2014
Pickrell WO, Lacey AS, Thomas RH, Lyons RA, Smith PE, Rees MI
PURPOSE: To investigate changes in the choice of first anti-epileptic drug (AED) and co-prescription of folic acid after a new diagnosis of epilepsy. METHODS: We searched anonymised electronic primary care reco...
Aug 26, 2014
Paul P, Agarwal M, Bhatia R, Vishnubhatla S, Singh MB
PURPOSE: India has an epilepsy treatment gap of up to 90%. Shortage of doctors, especially in rural communities makes getting epilepsy treatment almost impossible for the vast majority. Nurses are relatively more in nu...
Aug 22, 2014
Anderson GD, Hakimian S
Many factors influence choice of antiepileptic drugs (AEDs), including efficacy of the drug for the indication (epilepsy, neuropathic pain, affective disorder, migraine), tolerability, and toxicity. The first-generatio...
Aug 19, 2014
Wallander KM, Ohman I, Dahlin M
Background Zonisamide is a new generation antiepileptic drug (AED) widely used in children with refractory epilepsy, although until recently, it was used to a large extent as off-label or unlicensed medication due to t...