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Ninth Eilat Conference on New Antiepileptic Drugs (Eilat IX) / June 15 - 19, 2008

Sponsored by:

The Hebrew University of Jerusalem, Israel
The Hebrew University of Jerusalem, Israel
Epilepsy Theray Project

Epilepsy Therapy Project


Scheduled for June 15 – 19th in Sitges, Spain, the Eilat Conferences on New Antiepileptic Drugs (AEDs) is designed to provide an in-depth progress report on new antiepileptic drugs in different stages of development, as well as to present new findings on second-generation treatments. In addition, sessions will be devoted to:

  • Old and New AEDs in Generalized Epilepsies
  • Novel Formulations and Routes of Administration of AEDs
  • Common Targets and Mechanisms of Action of Drugs for the Treatment of Epilepsy and other CNS disorders
  • Perspectives on new AED discovery


Registration


Program

SATELLITE SYMPOSIUM
All registered participants of the Ninth Eilat Conference on New Antiepileptic Drugs (EILAT IX) are invited to participate in the Satellite Symposium which will be held at the Melia Sitges, the Conference Venue. Participation is on a "first come first served basis". Kindly mark your intention to participate on the enclosed Registration Form.

SUNDAY, JUNE 15, 2008

16:30 - 18:30 CARISBAMATE : Johnson & Johnson Satellite Symposium


MONDAY, JUNE 16, 2008

08:00 – 08:30 Opening Session : OPENING REMARKS AND GREETINGS

 


Session I
08:30 – 13:00
OLD AND NEW AEDs IN GENERALIZED EPILEPSIES | Chairpersons: E. Abadie (France), R. Katz (USA)
08:30 GENERALIZED EPILEPSIES: CLASSIFICATION, EPIDEMIOLOGY AND UNMET NEEDS | R. Guerrini (Italy)
08:50 Discussion
09:00 PREDICTING EFFICACY OF AEDs IN GENERALIZED EPILEPSIES | H.S. White (USA)
09:20 Discussion
Session I
08:30 – 13:00
CLINICAL TRIALS OF NEW AEDs IN GENERALIZED EPILEPSIES: TOO LITTLE, TOO LATE? DIFFERENCES IN PERSPECTIVES
09:30 Syndromes with onset in Early Childhood | O. Dulac (France)
09:50 Discussion
10:00 Syndromes with onset in Adolescence and Adults | K. Eriksson (Finland)
10:20 Discussion
10:30 Coffee
11:00 The Regulator | R. Katz (USA)
11:20 Discussion
11:30 The Pharmaceutical Industry | P. Verdru (Belgium)
11:50 Discussion
12:00 ORPHAN DRUGS FOR RARE SYNDROMES | C. Chiron (France)
12:20 Discussion
12:30 OLD AND NEW AEDs IN THE TREATMENT OF IDIOPATHIC GENERALIZED EPILEPSIES: REVIEW OF THE EVIDENCE AND PLACE IN THE TREATMENT ALGORITHM | P.H. Ryvlin (France)
12:50 Discussion
13:00 Coffee

 


Session II
13:30 – 15:00
NOVEL FORMULATIONS AND ROUTES OF ADMINISTRATION OF AEDs: INNOVATION | Chairpersons: S. Johannessen (Norway), P. Wolf (Denmark)
13:30 MODIFIED RELEASE FORMULATIONS OF AEDs: REAL PROGRESS OR MARKETING GIMMICK? | E. Trinka (Austria)
13:50 Discussion
14:00 Debate: SHOULD WE AVOID THE USE OF GENERIC PRODUCTS OF AEDs? | Pro: T.A. Pedley (USA) - Con: E. Perucca (Italy)
14:20 Discussion
14:30 WHAT IS THE BEST FOR EMERGENCY TREATMENT WHEN THE I.V. ROUTE IS NOT AVAILABLE? | J.C. Cloyd (USA)
14:50 Discussion


TUESDAY, JUNE 17, 2008

Session III - A
08:00 – 10:00
DRUGS IN DEVELOPMENT | Chairpersons: M. Bialer (Israel), R.H. Levy (USA)
08:00 BRIVARACETAM (ucb 34714) | P. von Rosenstiel, UCB S.A., (Belgium)
08:20 Discussion
08:30 CARISBAMATE (RWJ-333369) | G.P. Novak, Johnson &Johnson Pharmaceutical Research & Development (USA)
08:50 Discussion
09:00 2-DEOXY-GLUCOSE | Presented by T.P. Sutula, University of Wisconsin (USA)
09:20 Discussion
09:30 ESLICARBAZEPINE ACETATE (BIA 2-093) | BIAL - Portela & Cª., S.A. (Portugal), presented by E. Ben Menachem, University of Goteborg (Sweden)
09:50 Discussion
10:00 Coffee
10:30 – 12:30 DRUGS IN DEVELOPMENT | Chairpersons: E. Perucca (Italy), H.S. White (USA)
10:30 FLUOROFELBAMATE | B.A. Roecklein, MedPointe Pharmaceuticals (USA)
10:50 Discussion
11:00 GANAXOLONE | V. Pieribone, Marinus Pharmaceuticals (USA)
11:20 Discussion
11:30 HUPERZINE | Presented by S. Schachter, Harvard Medical School (USA)
11:50 Discussion
 
Session III - B
10:30 – 12:30
DRUGS IN DEVELOPMENT
12:00 LACOSAMIDE (SPM 927) | T. Sullivan, Schwarz BioSciences (USA)
12:20 Discussion
12:30 Lunch
 
Session III - C
14:00 – 15:30
DRUGS IN DEVELOPMENT | Chairpersons: S.I. Johannessen (Norway), H.J. Kupferberg (USA)
14:00 NAX 5055 | NeuroAdjuvants (USA), presented by G. Bulaj, University of Utah (USA)
14:20 Discussion
14:30 RETIGABINE | H. Mansbach, Valeant Pharmaceuticals (USA)
14:50 Discussion
15:00 SELETRACETAM (ucb 44212) | B. Bennet, UCB Pharma (USA)
15:20 Discussion
15:30 Coffee
 
Session III - D
16:00 – 19:30
DRUGS IN DEVELOPMENT | Chairpersons: B. Schmidt (Germany), T. Tomson (Sweden)
16:00 T2000 | Presented by M. Gasior, Cephalon, Inc. (USA)
16:20 Discussion
16:30 TONABERSAT | P. Blower, Minster Pharmaceuticals plc (UK)
16:50 Discussion
17:00 VALROCEMIDE | Presented by M. Bialer, The Hebrew University of Jerusalem (Israel)
17:20 Discussion
17:30 JZP-4 | M. Foreman, Jazz Pharmaceuticals, (USA)
17:50 Discussion
18:00 PROPYLISOPROPYL ACETAMIDE (PID) | Jazz Pharmaceuticals (USA), presented by M. Bialer, The Hebrew University of Jerusalem (Israel)
18:20 Discussion
18:30 VALNOCTAMIDE STEREOSOMERS | Presented by R.H. Farber, Neurocrine Biosciences (USA), and M. Bialer, The Hebrew University of Jerusalem (Israel)
18:50 Discussion
19:00 YKP3089 | S.J. Lee, SK Life Science, New Jersey (USA)
19:20 Discussion


WEDNESDAY, JUNE 18, 2008

Session IV - A
08:00 – 10:30
PROGRESS REPORT ON SECOND-GENERATION TREATMENTS | Chairpersons: I. Leppik (USA), M. Neufeld (Israel)
08:00 FELBAMATE | B.A. Roecklein, MedPointe Pharmaceuticals (USA)
08:20 Discussion
08:30 GABAPENTIN | Presented by B. Schmidt, Wittnau (Germany)
08:50 Discussion
09:00 LAMOTRIGINE | Presented by F.M.C. Besag, Twinwoods Health Resource Centre Bedfordshire & Luton Institutes of Psychiatry and Child Health (UK)
09:20 Discussion
09:30 LEVETIRACETAM | F. Tonner, UCB S.A. (Belgium)
09:50 Discussion
10:00 OXCARBAZEPINE | Presented by C. Elger, University of Bonn (Germany)
10:20 Discussion
10:30 Coffee
 
Session IV - B
11:00 – 13:30
PROGRESS REPORT ON SECOND-GENERATION TREATMENTS | Chairpersons: M. Baulac (France), P.H. Ryvlin (France)
11:00 PREGABALIN | Pfizer Inc. USA, presented by B. Uthman, University of Florida and McKnight Brain Insitute (USA)
11:20 Discussion
11:30 RUFINAMIDE | A. Yeates, Eisai Europe Ltd (UK)
12:00 STIRIPENTOL | Presented by C. Chiron, Necker-Enfants Malades Hospital, Paris (France)
12:20 Discussion
12:30 TIAGABINE | Presented by R. Kälviäinen, Kuopio University Hospital (Finland)
12:50 Discussion
13:00 TOPIRAMATE | S. Ness, Johnson & Johnson Pharmaceutical Research & Development (USA)
13:20 Discussion
13:30 Lunch Break
 
Session IV - C
14:30 – 17:00
PROGRESS REPORT ON SECOND-GENERATION TREATMENTS | Chairpersons: C.E. Elger (Germany), S. Shorvon (UK)
14:30 VIGABATRIN | S. Collins, Ovation Pharmaceuticals, Inc (USA)
14:50 Discussions
15:00 ZONISAMIDE | R. van Maanen, Eisai Ltd (EGC) (UK)
15:20 Discussions
15:30 OXCARBAZEPINE MODIFIED-RELEASE (MR) FORMULATION | Desitin Arzneimittel GmbH (Germany), presented by B.J. Steinhoff, Epilepsy Center Kork (Germany)
15:50 Discussion
16:00 VALPROIC ACID (DIVALPROEX SODIUM) EXTENDED-RELEASE (ER) FORMULATION | R.C. Reed, Abbott Laboratories (USA)
16:20 Discussion
16:30 LAMOTRIGINE EXTENDED RELEASE (ER) FORMULATION | K. Vanlandingham, GlaxoSmithKline (USA)
16:50 Discussions


THURSDAY, JUNE 19, 2008

Session V
08:30 – 12:00
COMMON TARGETS AND MECHANISMS OF ACTION OF DRUGS FOR THE TREATMENT OF EPILEPSY AND OTHER CNS DISORDERS: IS THERE AN OVERLAP? | Chairpersons: E. Perucca (Italy), T. Tomson (Sweden)
08:30 EPILEPSY AND NEUROPATHIC PAIN | M. Devor (Israel)
08:50 Discussion
09:00 EPILEPSY AND BIPOLAR DISORDERS | A. Harwood (UK)
09:20 Discussion
09:30 EPILEPSY AND MIGRAINE | M.A. Rogawski (USA)
09:50 Discussion
10:00 Coffee
10:30 EPILEPSY AND ADDITIONAL CNS DISORDERS | S. Shorvon (UK)
10:50 Discussion
11:00 THE UTILIZATION OF AEDs IN NON-EPILEPTIC CNS DISORDERS-CLINICAL PERSPECTIVES | A.M. Kanner (USA)
11:20 Discussion
11:30 TOWARDS A BETTER UNDERSTANDING OF AED SITES OF ACTION: IMAGING EVALUATION OF ANTIEPILEPTIC DRUGS | W.H. Theodore (USA)
11:50 Discussion
 
Session VI
12:00 – 14:00
OPPORTUNITIES AND PERSPECTIVES IN NEW AED DISCOVERY | Chairpersons: R. Twyman (USA), H.S. White (USA)
12:00 CREATING OPPORTUNITIES TO FUND NEW THERAPIES FOR EPILEPSY | J. Cramer, Epilepsy Therapy Development Project (USA)
12:20 Discussion
12:30 CURRENT PERSPECTIVES IN NEW AED DISCOVERY | PANEL DISCUSSION
  • H. Klitgaard, UCB Pharma (Belgium)
  • S. Schwabe, Sanofi-Aventis (USA)
  • R. Twyman, Johnson & Johnson Pharmaceutical Research & Development (USA)
  • H.S. White, University of Utah & Anticonvulsant Screening Program (USA)
  • M. Bialer, The Hebrew University of Jerusalem (Israel)
14:00 Closing Remarks | S.I. Johannessen (Norway)
16:00 – 20:00 Satellite Symposium - CEA-SPONSORED SYMPOSIUM ON EMEA GUIDELINES FOR NEW AEDs | Chairpersons: E. Abadie (France), M. Baulac (France)


Organizing Committee:

  • Meir Bialer, Jerusalem, Israel
  • Svein I. Johannessen, Sandvika, Norway
  • Rene H. Levy, Seattle USA
  • Emilio Perucca, Pavia, Italy
  • Torbjörn Tomson, Stockholm, Sweden
  • H. Steven White, Salt Lake City, USA


Travel and Accommodations

Target Conferences is the official travel agent for the Ninth Eilat Conference on New Antiepileptic Drugs and will be offering special reduced rates for accommodation and conference tours.

Target Conferences Ltd.
PO Box 29041, Tel Aviv 61290, Israel
Tel: +972 3 5175150, Fax +972 3 5175155
E-mail: eilatix@targetconf.com

For more travel information, including hotel, air travel and transportation to/from conference venue: click here.


Conference Secretariat

If you require any additional information or assistance, please contact the Secretariat:

Ninth Eilat Conference on New Antiepileptic Drugs (Eilat IX)
PO Box 29041, Tel Aviv 61290, Israel
Tel: +972 3 5175150, Fax: +972 3 5175155
e-mail: eilatix@targetconf.com

To view detailed conference information, please visit: www.Eilat-aeds.com