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The Pipeline Wiki is a resource created and edited by the epilepsy community intended to offer a comprehensive and up-to-date review of every drug or device under development. Our Pipeline Conferences foster relationships and collaboration among scientists, researchers, entrepreneurs, investors, patients, philanthropists and established companies. We hope our Pipeline Wiki will accomplish the same objectives and contribute towards making these exciting ideas a reality as therapies for patients.

Drugs

admin Bio-Link, dynamin inhibitors Createdat9/2/10 - 1:04 pm ...
admin Catalyst, CPP-115 Createdat9/2/10 - 1:08 pm Tx name CPP-115 Description GABA transaminase inhibitor Company Catalyst Status   Overview
admin Ganaxolone Createdat9/2/10 - 1:08 pm Philanthropic Funding Provided by: Epilepsy Therapy Project Tx name Ganaxolone Description Neurosteroid Company Marinus Status Phase 2 Overview
admin MediPro Pharma, MPP-021 Createdat9/2/10 - 1:09 pm Philanthropic Funding Provided by: Tx name MPP-021 Description
admin MedKura, Inhaled propofol Createdat9/2/10 - 1:09 pm Philanthropic Funding Provided by: Epilepsy Therapy Project. Tx name Inhaled Antiseizure Treatments Description Inhaled propofol for treatment of acute seizures Company Medkura Status
admin NeuroGenomeX, 2-DG Createdat9/2/10 - 1:10 pm ...
admin Neurotherapeutics, NTP 2014 Createdat9/2/10 - 1:10 pm Philanthropic Funding Provided by: Epilepsy Therapy Project. Tx name NTP-2014 Description Novel MOA Company Neurotherapeutics Status Preclinical Overview
dfried36 Paloma, P529 Dual-TORC inhibitor Createdat4/12/11 - 8:30 pm Tx name P529 Description Dual TORC inhibitor Company Paloma Status   Overview
warren7 Perampanel Createdat2/1/11 - 1:31 am Perampanel (E2007) Summary: Perampanel is a first-in-class AMPA-type glutamate receptor antagonist being developed by Eisai for partial onset seizures. Three global Phase III studies have been completed including 1490 patients, and Eisai indicated...
admin Retigabine Createdat8/16/10 - 2:26 pm Retigabine Summary:
admin SK Life Sciences, YKP 3089 Createdat9/2/10 - 1:12 pm Tx name YKP3089 Description efficacy for epilepsy, pain, bipolar, anxiety Company SK Life Sciences Status   Overview

Devices

admin BioLert, Seizure Alert Device Createdat9/2/10 - 1:13 pm Tx name CPP-115 Description GABA transaminase inhibitor Company Catalyst Status   Overview
siappl... CortiFlex Headset Createdat9/10/10 - 9:48 pm Tx name Wireless EEG electrode cap Description ANI Headset (Electrode Cap ) Company Advanced Neurometrics, Inc. Status Phase 1 Overview
dboison Legacy, Adenosine Implant Createdat9/8/10 - 9:09 am Tx name Adenosine-releasing silk-based brain implants for epilepsy therapy Description Adenosine delivery to brain Company Legacy Hospital System Status   Overview
admin NeuroVista, Seizure Advisory System Createdat9/2/10 - 1:14 pm Tx name Seizure Advisory System Description Implanted device warns when EEG activity signals a likely seizure Company NeuroVista Status First patient implanted in Australia July 2010
warren... SmartWatch by Smart Monitor Corporation Createdat10/5/10 - 9:57 am Philanthropic Funding Provided by: Epilepsy Therapy Project. Product Name SmartWatch Description Wearable Seizure detection and alert monitor Company Location Smart...
aschulz Visualase, Image-guided Laser Technology for Thermal Ablation Createdat11/29/11 - 7:15 pm Tx name Laser Ablation in Epilectic Foci Description Image-guided Laser Technology provides minimally invasive thermal ablation Company Visualase Overview

Other

admin Asklepios, galanin gene therapy Createdat9/2/10 - 1:15 pm Philanthropic Funding Provided by: Epilepsy Therapy Project Tx name Galanin Description Gene therapy Company Asklepios Status Pre-clinical Overview
admin CanCog, Canine Model Createdat9/2/10 - 1:16 pm Tx name A Naturally Occurring Dog Model of Epilepsy Description Proof of concept testing in dogs with epilepsy; Dog model has value as a translational model prior to human clinical trials because of the genetic...
admin Neurologix, NPY gene therapy Createdat9/2/10 - 1:16 pm Tx name NPY gene therapy Description In vivo NPY gene transfer allows for high level expression and functional efficacy limited to target region in the temporal lobe Company Neurologix Status Primate...