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New Form of Lamictal Approved

Lamictal®-XR (for extended release) has been approved by the FDA for epilepsy therapy as a single daily dose. Approval was for adjunctive (add-on) therapy to other anti-seizure medicines in people age 13 years or older who have partial onset seizures with or without secondary generalization. Common side effects of Lamictal®-XR were headache (though not more than in patients taking a placebo pill), nausea and vomiting, fever, dizziness, double vision, tremor, anxiety and rash (in 3%). The single daily dose of Lamictal®-XR can be the current total daily dose in milligrams. There is a generic form of Lamictal®, which is lamotrigine, but no generic form yet exists for Lamictal®-XR as a single daily dose medicine. Once-a-day medication may make it easier to remember to take the medicine (see http://www.epilepsy.com/epilepsy/medication_compliance)

Robert S. Fisher, M.D., Ph.D.
Editor-in-Chief, epilepsy.com


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