i started taking Zonegran when i got diagosned with E. I lost a lot of weight, had memory problems, confusion, and always slept, almost all day. those all lasted about 5 months or so.

overall, its been working well for me. and the seizures are better.

good luck.

Gabi.

Hi,

I've been on Zonegran since 2003. I'm also on Lamictal, trileptal, have a VNS, and just started a new drug trial last week.

ANYWAY, I'm on zonegran and I've had fairly good results from it. It has helped me with seizure controll. The biggest side effects that I have had to deal with have been the weight loss, nausia, and memory issues (but trileptol  and Lamictal dont  help that).

I'm very very sensitive to side effects of medications, kinda sucks. I've had to regulate my diet to keep my weight at a steady 120. My Neuro Doc (who I completely trust) tells me that my drastic weight loss is not the norm.   The nausia seemed to decline after the first 7 months, it wasn't terrible.

For me Zonegran has helped a great deal and a think that the benifits have outweighed the side effects.  I havent had the extreem sleepiness or moodiness/ depression that I've delt with in other ddrugs.

Since I'm now at a good med level for me the side effects have subsided to being manageable or un noticeable.

I hope i've been a help to you.

Good luck to you I hope you find a solution to get your seizures under controll, I'm around if you need anything else.  :)

  ~Amanda Lynn~

I just started the transition from Keppra (3000 mg/day) to zonisamide (generic Zonegran) a few days ago.  I am hopeful that this will work.  The Keppra was not controlling the simple partial seizures.  So far, I am feeling ok but still having the simple partials.  I want to give it a little longer before I talk to my neurologist.  I would also love to hear anyone else's experience with this.  Take care!