Medication causing a Seizure?

Hi Everyone. I am the mom to a 16 year old girl that I adopted at age 1. There is no known family history for my daughter. She has cerebral palsy. At age 5, after taking an antihistamine she had what appeared to me as a seizure, although I thought that because her eyes had rapid movement horizontally. A few  years later I learned that she has nystagmus and when she becomes sick this condition is more obvious, so perhaps that is what I saw. BUT based solely on my description of what I saw, she was sent to a neurologist who diagnosed her with partial complex seizures. She took a wait and see approach and did not put her on anti-seizure meds. She said it was not likely that the antihistamine brought on the seizure. I never gave her an antihistamine again. She never had a similar episode during her elementary school years.

Leap ahead to this past July. She is now 16 and for the itchiness that comes with eczema her pediatrician prescribed Hydroxyzine. Later that month she had an "incident" at school (she goes to school year round) and the teachers not knowing what might be going on, called 911 and they wisked her off to Children's Hospital. When I got there (within the hour) she was fine, but the teachers said she had been disoriented, talking slowly and her eyes were moving horizontally back and forth quickly. Children's did a pregnancy test and when it came back negative determined she was fine -- and at that point she WAS fine. They did not do an eeg but said it could have been a seizure. At that time I didn't think about the Hydroxyzine. She slept the rest of the day and night and the next day everything was back to normal.

It is now winter and she started up with the Hydroxyzine last week because of an eczema flair up. Yesterday she had a similar incident at school. Since a doctor has never seen it -- it was my description the first time and the teachers' description the second time, I took her immediately to her pedicatrician's office. One said she wasn't presenting like it was a seizure, another said he thought it was a partial complex seizure (which is what was written in her file from when she was 5). She was able to talk, answer all their questions. She was noticably tired and shivering and had some involuntary arm and leg movements. They sent her by ambulance to Children's. She slept on the way there and up until the first ER doctor came in to see her, so a total of 1.5 hours. When they woke her up she was groggy but fine -- no longer shaking and answering questions faster and easier than earlier. The ER doctors did a pregnancy test, a blood sugar test, a test for drugs in her system. After it all they determined she was a bit dehydrated. They said it could have been a seizure but since they didn't see her until she was fine, they didn't know. I had a lot of this episode on video via my phone and upon looking at it they still did not know. No eeg was done but they thought maybe she should do a video eeg in the near future. She has had one eeg and one video eeg in the past and both were clear -- which of course I know doesn't mean that she has never seized -- just wasn't at the time of the eeg.

So my question -- does anyone know if Hydroxyzine has a connection with seizures? When I look online it says it can "cause involuntary muscle movements"....so, not sure. The pediatrican says there is NO correlation. I have a call into my daughter's neurologist to see what she thinks.

My concern is that they may now begin to treat her as a seizure patient when it might only be drug-enduced seizures. Having a kid with CP, I have noticed that a lot of doctors don't seem to consider that my child has an already compromised body, and what might not be a factor in 99% of the population, *might* be with a person with a condition like hers.

So, does anyone have any thoughts about this? These episodes are scary, but after sleeping a few hours she is always fine. Of course we are talking about 3 episodes in her lifetime, not dozens or hundreds. So there isn't a lot to work with. But the fact that she has had 2 in six months is what has her doctors jumping to now thinking she should be on anti-seizure meds. Thanks for reading and for your input.