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lamictal, edema, eosophinils, long term use

Wed, 07/29/2015 - 15:08
I don't  have epilepsy but I've been on 150mg lamotrigine 9 years for bipolar after having a manic episode  (the only one ever).  I'm also on venlafaxine (37.5mg 2 x a day) for 11 years and zoloft (50mg) for 10 years before that. In the last year and a half I've had pitting & non-pitting edema in my legs, feet & ankles, hypersensitvity of my shins, muscle weakness  and swelling & contracture in my hands (prayer hands).  Memory loss (forgetting words and focus of conversations), and elevated white blood cells (eosinophilia). I want to get off of Lamictal because I've read of the connection between my symptoms & the drug.  Has anyone found any studies of long term use & problems with lamictal?  

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