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Medication side effects (Lamictal / Keppra)

Thu, 05/07/2015 - 22:48

Hello.  This is my first post here and I hope I am posting in the appropriate section.

To give you some of my background, I had my first known seizure at the age of ~ 8 (I was not on anti-epileptic medication up until then), another at 15 (was on Dilantin), another at 26 (not on medication).  I should say that I began taking Dilantin as a result of the seizure at age 8, and my doctor took me off anti-eplieptic meds at age 19 as he felt I did not need them (I stopped taking Dilantin on my own which I know I shouldn't have but did anyway, so I essentially played my own doctor and had no anti-epileptic drugs from 17 to 19).  When I had the most recent seizure at age 26 I was in a casino and was staring at a machine that triggered it (the age 15 and 26 seizures were set off by computurized flashing of some sort).   I knew the thing that triggered them was rapid flashing/computer screens, etc.  I avoided them as best as I could and foolishly thought when the doctor told me I didn't have to take medicine anymore that maybe I had "outgrown" epilepsy.  The episode at age 26 proved me wrong.

After the last seizure, between ages 26 - 31 I was back on Dilantin.  I had asked my doctor to get me off of Dilantin because I read of various side effects.  He told me he was comfortable with having me switch to Keppra, but warned me of the aggression side effect some patients exhibit.  Fortunately I had no problems with rage or frustration.  No seizure breakthroughs while on Keppra.

I asked my doctor about a year ago (age 32) if there was another medication that could help with social anxiety and "brain fog" (I think it's called? when your mind and overall thought processes are slowed, as if there's some sort of lag?) I had seemed to develop towards the end while being on Keppra.  He told me I should consider Lamictal, so I switched.  No seizure breakthrough, and there's been some improvement with social anxiety and hardly any with brain fog and having difficulty remembering things (no major memory issues, but definitely memory is not as good as I remember it being, especially when I wasn't taking any meds between 19 - 26).

Okay, so here's my main question:  

When I switched from Dilantin to Keppra, and then when I switched from Keppra to Lamictal, there was a very interesting transition period, cognitive function wise.  I'm going to try to explain it as best as I can: When I transitioned I felt an elevated level of awareness, cognitive function, and memory.  It was as if the cloud had been lifted, my memory was amazingly good, social anxiety zero, and my ability to THINK and PROCESS info (basically function) was multiplied by at least a factor of 10, I am not exaggerating.  I felt better than I had ever felt before, and when I first felt this way after switching from Dilantin, I thought I had found the perfect answer to my problems.  Unfortunately the effect wore off after 6-9 months.  The fog slowly krept back, and then I went back to my doc to inquire about a new drug, Lamictal.  When I made the transition to Lamictal from Keppra, I had the same positive transition effects, but it wasn't the same as Keppra... it was shorter lived and ontop of that I felt some minor odd numbness/slight dizziness sensations during the first month of loading phase.

I want to be clear on this improved cognitive function I am talking about.  For example, I remember specifically lying in bed, falling asleep, and during some point of my sleep, I was aware of my thoughts (not dreamking) thinking of mathimatical problems I was used to solving before, but this time I was calculating things in lightning speed, thinking/solving anything number related, my brain was thinking so fast and efficiently, it was almost scary and I felt I needed to throttle back some how (but of course how could I, it wasn't as if I was flexing a muscle too hard or something, it was simply rapid thought).  Ever watch Star Trek TNG when Barclay became smarter and took over for the computer of the Enterprise?  That was me. (btw I'm a total geek lol)

Anyway to summarize, I had what felt was perfect mental ability/efficiency and there was simply no limit as to what I could think and do.  My confidence was unlimited, anything I thought I could do I did.  It sounds almost like a high, but the difference of course is I had complete control and nothing was dangerous.  As an example, I would talk with my wife, she would say things and I would be able to remember almost exactly every word she said.  We would have an argument and I could respond back repeating every single point she brought up and then be able to adequately respond and logically point out my stance on whatever the topic happened to be and explain my position, thoughts, etc (argue).  Now for example, I have a very difficult time recalling specific things brought up in a conversation, and if I need to explain my reasoning/opinion on something, it's nearly impossible because I can't remember the chain of discussion and it's very difficult for me to THINK and articulate myself (at least compared to before) so I've unfortunately turned into a very passive, giving up, lazy sort of person which I absolutely hate, especially since I have memory of being quite different. (ignorance is bliss, right?)

Have any of my fellow epileptics out there ever experienced something like this?  Are there any neurologists/experts out there who might be familiar with this sort of thing and perhaps be able to offer me insight on what exactly happened when I transitioned from one drug to another?  If I wanted to regain this hightened sense of cognitive functioning, is it possible?  Could my dosage have been too low/high on Lamictal?

Any helpful responses are very much appreciated.  If you need any additional information or more specifics please let me know.  

I sincerely appreciate you taking the time to read this.

Best,

~Saffy

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