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Max. allowable dose of lamictal

Fri, 11/19/2010 - 11:36
In scanning several threads, I've noted that many people are on fairly high doses of lamictal (whether or not combined with other drugs). The highest dose I've read about so far in this forum is 450 mg. I am currently on 200 mg, and potentially will be increased to 250 - 300 mg. I've read that at doses of 300 mg. and higher that lamictal is being used as a med for bipolar (and perhaps depression, but I'm not sure). I definitely don't have either of those conditions, and probably none of you taking these higher doses does either. This leads me to the following questions: 1. What is the max allowable dose of lamictal? 2. Do higher levels of lamictal offer even greater seizure control? PLEASE correct me if I'm wrong, but I thought lamictal's effectiveness for controlling seizures "plateaued" once you reached 300 mg, and that's why at these higher doses it is considered a bipolar drug rather than an AED. Thanks in advance for any help!

Comments

Re: Max. allowable dose of lamictal

Submitted by Masterjen on Sat, 2012-06-30 - 14:18
Would love to hear how you find the Vimpat. Since my initial post: I was taken off lamictal about a year ago and put on a combo of tegretol and keppra, fairly low doses of each due to side effects if doses too high (double vision on tegretol and worsening of seizures on keppra). They aren't controlling the seizures, and dr, wants to try me on combo with vimpat. Not sure yet which one she is going to take me off of, tegretol or keppra. Anyway, it is always a bit unsettling to start an entirely new med. Let me know how you do!

Re: Max. allowable dose of lamictal

Submitted by just_joe on Thu, 2013-08-15 - 15:37

I have been taking th maxium amount of Keppra for many year. When they came out with the generic I wanted to try it and my neuros assistant was against it, However my neuro asked if I would mind trying it. I have used 4 different generic keppras and they have all worked well. I was having a higher seizure count than I liked and talked to him about it and I told him I thought it might have been the generic I was taking. He excuesed himself and went out and checked files. When he came back he said he didn't think it was the generic keppra which gave me the increase in seizures. I told him that the last 3 months I had had more seizures. He also said I had not been in drug studies for those 3 months and the 1 1/2 years I had been in studies I was taking a new medicine which is why the count was down. He added vimpat to the keppra I tak and now the seizure count is lower and the time in th seizure and focus time are also down. 750mr 3 morning and evening of keppra and 100 mg vimpat morning and night. I see him nexy month and will be taking my diary. I have been on this combination for 2 1/2 months plus the time to get to th dosagee he wants me on.

Vimpat has been good and it is made by the same company as keppra. The only side effects I have had were while getting up to the dosage and that was blurded vision which lasted a few seconds. twice

I have been taking th maxium amount of Keppra for many year. When they came out with the generic I wanted to try it and my neuros assistant was against it, However my neuro asked if I would mind trying it. I have used 4 different generic keppras and they have all worked well. I was having a higher seizure count than I liked and talked to him about it and I told him I thought it might have been the generic I was taking. He excuesed himself and went out and checked files. When he came back he said he didn't think it was the generic keppra which gave me the increase in seizures. I told him that the last 3 months I had had more seizures. He also said I had not been in drug studies for those 3 months and the 1 1/2 years I had been in studies I was taking a new medicine which is why the count was down. He added vimpat to the keppra I tak and now the seizure count is lower and the time in th seizure and focus time are also down. 750mr 3 morning and evening of keppra and 100 mg vimpat morning and night. I see him nexy month and will be taking my diary. I have been on this combination for 2 1/2 months plus the time to get to th dosagee he wants me on.

Vimpat has been good and it is made by the same company as keppra. The only side effects I have had were while getting up to the dosage and that was blurded vision which lasted a few seconds. twice

Re: Max. allowable dose of lamictal

Submitted by Gallie on Thu, 2012-11-01 - 13:27

I am on that same combination: Vimpat, Potiga and Lamictal.I take everything 3 times a day. I am on a boatload of Lamictal (800mg), pretty much at the max of Vimpat (600mg), and at adose of Potiga that still has a lot of wiggle room to increase if need be (450mg).

These have been good drugs for me.

Lamictal was the second drug I was started on after Tegretol wasn't working very well when I was first diagnosed in high school. It doesn't seem to help much unless it is at such a high dose, but it is tough to deal with the drugginess.

I had a beautiful honeymoon period on Vimpat (3 months- a record), then the seizures came back but a little less often.

Potiga has been great. In four months, I have had two seizures, and they were much less severe (I have secondarily generalized). Instead of being wasted all day the next day, I feel a little better, and can do some stuff.

Potiga looks promising.

But with this combination, for an hour or so an hour after I take each dose, three times a day, I get really "druggy." Blurry vision, a little bit clumsy, and absolutely lusting for sleep.

BUT- it's getting better.

I am on that same combination: Vimpat, Potiga and Lamictal.I take everything 3 times a day. I am on a boatload of Lamictal (800mg), pretty much at the max of Vimpat (600mg), and at adose of Potiga that still has a lot of wiggle room to increase if need be (450mg).

These have been good drugs for me.

Lamictal was the second drug I was started on after Tegretol wasn't working very well when I was first diagnosed in high school. It doesn't seem to help much unless it is at such a high dose, but it is tough to deal with the drugginess.

I had a beautiful honeymoon period on Vimpat (3 months- a record), then the seizures came back but a little less often.

Potiga has been great. In four months, I have had two seizures, and they were much less severe (I have secondarily generalized). Instead of being wasted all day the next day, I feel a little better, and can do some stuff.

Potiga looks promising.

But with this combination, for an hour or so an hour after I take each dose, three times a day, I get really "druggy." Blurry vision, a little bit clumsy, and absolutely lusting for sleep.

BUT- it's getting better.

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