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Depakote, Behaviors, and personality

Mon, 02/11/2008 - 19:22
My 7 year old daughter was diagnosed with Epilepsy a year ago this coming April.  She has been on Depakote since the beginning.  It seems to be doing very well at controlling the seizures, but she has become a whole different child.  It breaks my heart, and every day seems to get a little bit worse.  She is regressing academicaly, socially, and emotionally.  Her neuro seems to think it is all "behavior issues".  He doesn't want to change the meds but has mentioned it a couple of times.  He seems to think she will be like this no matter what we put her on.  I want my little girl back.  Anybody else struggling with this?

Comments

Re: Depakote, Behaviors, and personality

Submitted by sophiesmom on Mon, 2008-03-10 - 06:59
I've heard about the potential for rash with Lamictal, but still good to know.  Thanks a lot for the info!  It sounds like it's working well for you...and I hope the appointment with your other doc goes well.  I just went for my 3rd consult in a couple of years - always trying to find the magic bullet (which doesn't exist).  I also have to nap most days, no matter what meds I'm on.  As to your twitches, they sure sound like myocolonic seizures, which I have ALL the time.  Klonopin has helped that a lot - at least for me.  Thanks again for sharing your information.

Re: Depakote, Behaviors, and personality

Submitted by dlynn2 on Thu, 2008-03-27 - 13:19
Sophie, I have been on Depakote for 20 years with minimal to no side effects. I did change medications before and during my pregnancy to Lamictal but I did have several seizures while I was on Lamictal and following the birth of my twins my doctor switched me back to Depakote ER (500 MG/day). Again no major side effects. No mood changes, weight gain. The only thing I really experience is being a little tired, but I don't directly relate that to the meds. Every person has a different reaction to medicine so the only thing you can do it try and if it doesn't work or you have side effects then ask your doctor to change you. Hope this helps.

Re: Depakote, Behaviors, and personality

Submitted by ValNewLife on Fri, 2008-03-07 - 16:30

My son had a major personality change on Lamictal.  With each dose increase he became increasingly aggressive and angry...not like himself at all.  I continued to call his Neurologist's office and their reply was always the same "Well, that's not typical of Lamictal. Lets get him to therapeutic level and see what happens."  So we kept waiting, and increasing, and my son kept getting worse.  After some terrifying events, my son ended up in the hospital "detoxing" from the lamictal.  It was the hardest thing we've ever been through...and all along the Neurologists continued to say "It wasn't the Lamictal"!  Even as my son got better with each day he was off the med!  Oh, I could go on and on with our nightmare, but what I learned was this...

Every person reacts differently to every drug...period...whether it's "typical" or not.  You know your daughter best and if your Neurologist is not listening to you, then find another one.  It took a couple of tries before we found a Neurologist who really listened to us, and didn't want to just put our son in a "box" with everyone else.  

It's a very difficult and scary time, but you just have to keep moving forward.  My son is now on Topamax and is his old sweet, sensitive, funny self...but it took quite a while to get back to this point!  It breaks my heart to read your words because I've been there...but you will get through it!

One more thing, we did find a very good counselor for our son to help him with everything he had been through, and it has been such a blessing for him, and for us!  Our son is 12 and his counselor continues to help him deal with having E as well as other things, so that may be a possibilty too.  Go with your gut!

My son had a major personality change on Lamictal.  With each dose increase he became increasingly aggressive and angry...not like himself at all.  I continued to call his Neurologist's office and their reply was always the same "Well, that's not typical of Lamictal. Lets get him to therapeutic level and see what happens."  So we kept waiting, and increasing, and my son kept getting worse.  After some terrifying events, my son ended up in the hospital "detoxing" from the lamictal.  It was the hardest thing we've ever been through...and all along the Neurologists continued to say "It wasn't the Lamictal"!  Even as my son got better with each day he was off the med!  Oh, I could go on and on with our nightmare, but what I learned was this...

Every person reacts differently to every drug...period...whether it's "typical" or not.  You know your daughter best and if your Neurologist is not listening to you, then find another one.  It took a couple of tries before we found a Neurologist who really listened to us, and didn't want to just put our son in a "box" with everyone else.  

It's a very difficult and scary time, but you just have to keep moving forward.  My son is now on Topamax and is his old sweet, sensitive, funny self...but it took quite a while to get back to this point!  It breaks my heart to read your words because I've been there...but you will get through it!

One more thing, we did find a very good counselor for our son to help him with everything he had been through, and it has been such a blessing for him, and for us!  Our son is 12 and his counselor continues to help him deal with having E as well as other things, so that may be a possibilty too.  Go with your gut!

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