Understanding Risk of Rash from Seizure Medication

Epilepsy News From: Wednesday, May 11, 2016

The possibility of side effects or allergic reactions to seizure medications are a major concern for people with epilepsy. Researchers at the University of Pennsylvania are conducting a study to understand if there is a genetic link between the use of a seizure medication (Aptiom® or eslicarbazepine acetate) and the potential to develop severe skin reactions that can cause blisters, peeling of the skin, and open sores.

The researchers are looking for people who have taken this medication for at least 6 weeks and have not had a skin rash to volunteer for this study.

  • A sample of saliva will be collected so the researchers can look at your DNA (also called Deoxyribonucleic Acid, which contains the genetic instructions found in our bodies that determine how we may look, behave, and react to different things like medications). The saliva sample will not be associated with any of your personal information and is only used for this study.
  • Volunteers will also be asked about their family and medical history, including information on any skin conditions and reactions to medications.
  • The study will only take about 30 minutes of your time.

To learn more about this study, please contact:

David J Margolis, MD, PhD
Professor of Dermatology
215-662-2408 (phone)
maryte.papadopoulos@uphs.upenn.edu (email for research associate)

Reviewed Date

Wednesday, May 11, 2016

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